冠心病患者血清胆红素与尿酸以及C-反应蛋白的检测意义

目的探讨冠心病（CHD）患者血清总胆红素（TB）、尿酸（UA）、C-反应蛋白（CRP）的含量变化及临床意义。方法对73例CHD患者（单支病变28例、多支病变45例）及65例健康对照者进行血清TB、UA、CRP检测，然后进行CHD组与对照组、CHD组内单支病变组与多支病变组的TB、UA、CRP结果比对及分析研究。结果CHD组与对照组比较：TB明显下降，差异有统计学意义（P〈0．05）；UA及CRP明显上升，差异有统计学意义（P〈0．05）。CHD组内的多支病变组与单支病变组比较：TB明显下降，差异有统计学意义（P〈0．01）；UA明显上升，差异有统计学意义（P〈0．05）；CRP无明显变化，差异无统计学意义（P〉0．05）。结论低血清TB可能是CHD的危险因素之一，高UA、高CRP可能是导致CHD的主要因素，临床上应重视冠心患者TB、UA、CRP的检测。

Analytical study of the significance in detecting serum total bilirubin,uric acid, and C-reactive protein of the patients with coronary heart disease

Objective To discuss the changes of the contents of serum total bilirubin （TB）, uric acid （UA）, and C-reactive protein （CRP） in the patients with coronary heart disease （CHD） and its clinical significance. Methods An examination of total serum biliruhin, uric acid, and C-reactive protein is carried out on 73 patients with coronary heart disease （28 cases of one-vessel stenosis, 45 cases of multiple-vessel stenosis） and 65 normal controls, then the results of TB, UA, CRP of the CHD group and the control group, and those with one vessel stenosis group and multiple-vessel stenosis group in the CHD group are compared with each other, and the results are analyzed and studied. Results The content of TB is obviously smaller （P〈0.05）, and those of UA and CRP are obviously higher （P〈0.05） in the coronary disease group compared with the control group; The content of TB is obviously smaller （P〈0.01）, and that of UA is obviously higher （P〈0.05）, but there is of no obvious difference in the content of CRP （P〉0.05） in the multiple vessel stenosis group in the coronary disease group compared with the one of vessel stenosis group in the coronary disease group. Conclusion Low serum bilirubin content might be one of the CHD hazard factors; high UA content and high CRP content may be the primary factor to cause CHD; so much attention should be paid on the clinical examination of TB, UA and CRP in the patients with coronary disease.