Effect of the surgical technique on long-term outcome of pancreas transplantation |
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Authors: | Luis Carlos Feitosa Tajra Marwan Dawhara Mehdi Benchaib Nicole Lefrançois Xavier Martin J M Dubernard |
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Institution: | Department of Urology and Transplantation Surgery, H?pital Edouard Herriot, Place d'Arsonval, F-69 437 Lyon cédex 03, France Fax: + 33 4 7211 0582, FR
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Abstract: | To date there is no general consensus as to the best surgical technique for pancreas transplantation. Patients with a pancreas
transplant functioning for 3 years or more were retrospectively investigated to compare three surgical techniques: segmental
graft with duct obstruction (DO), whole graft with bladder drainage (BD), and whole graft with enteric drainage (ED). Several
parameters were studied: patient and graft survival, rejection, long-term surgical and medical complications, and endocrine
function. The best results in terms of graft survival and quality of metabolic control were obtained in the group that underwent
whole graft transplantation with ED. At 3 years, overall pancreas graft survival was 65 % for ED, 60 % for BD, and 47 % for
DO. This surgical method has become the preferred technique in our unit.
Received: 9 October 1997 Received after revision: 29 January 1998 Accepted: 30 March 1998 |
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Keywords: | Pancreas transplantation diversion Enteric diversion pancreas transplantation Bladder diversion pancreas transplantation |
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