| 黄芪对荷瘤小鼠TNF-α和IL-8水平的影响 |
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| 引用本文： | 曾肖芳,蓝梦颖,卢丹玉,陈永红,马秋琼,黄樊莹,李韬.黄芪对荷瘤小鼠TNF-α和IL-8水平的影响[J].右江民族医学院学报,2005,27(2):136-138. |
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| 作者姓名： | 曾肖芳 蓝梦颖 卢丹玉 陈永红 马秋琼 黄樊莹 李韬 |
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| 作者单位： | 1. 右江民族医学院2002级检验本科,广西,百色,533000
2. 右江民族医学院生物化学教研室,广西,百色,533000 |
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| 摘 要： | 目的 观察黄芪注射液对荷瘤小鼠血清中肿瘤坏死因子α(TNF -α)和白细胞介素-8(IL -8)水平的影响。方法 采用S180 荷瘤小鼠作肿瘤模型,给予黄芪注射液10d后观察荷瘤小鼠血清中TNF -α和IL -8的变化情况。结果 黄芪治疗组和对照组血清中的TNF -α明显高于非治疗组(P <0 .0 1) ,而IL -8明显低于非治疗组(P <0 .0 1)。结论 黄芪注射液能促进TNF -α的产生,降低IL -8的水平,对肿瘤细胞的杀伤和炎症的控制有一定的作用。
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| 关 键 词： | 黄芪 肿瘤 TNF-α IL-8 小鼠 动物 实验 |
| 文章编号： | 1001-5817(2005)02-0136-03 |
| 修稿时间： | 2004年9月20日 |
Effects of Astragali on the TNF-α and IL-8 of Tumor-bearing mice |
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| ZENG Xiao-fang,LAN Meng-ying,LU Dan-yu,CHEN Yong-hong,MA Qiu-qiong,HUANG Fan-ying,LI Tao.Effects of Astragali on the TNF-α and IL-8 of Tumor-bearing mice[J].Journal of Youjiang Medical College For Nationalities,2005,27(2):136-138. |
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| Authors: | ZENG Xiao-fang LAN Meng-ying LU Dan-yu CHEN Yong-hong MA Qiu-qiong HUANG Fan-ying LI Tao |
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| Institution: | ZENG Xiao-fang1,LAN Meng-ying1,LU Dan-yu1,CHEN Yong-hong1,MA Qiu-qiong1,HUANG Fan-ying1,LI Tao2 |
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| Abstract: | Objective To observe the effects of astragali injection on the change levels of the tumor necrosis factor α(TNF-α) and the interleukin-8(IL-8) of tumor-bearing mice. Methods S180tumor-bearing mice were used as tumor model. The tumor necrosis factor α(TNF-α) and the interleukin-8(IL-8) of the tumor-bearing mice were observed after ten days when astragali injection was given. Results The amounts of TNF-αin the astragali group and the control group were much higher that those of the non-therapy group(P<0.01)while the amounts of IL-8were significantly lower than the non-therapy group(P<0.01). Conclusion Astragali injection could help produce TNF-αand lower the IL-8level and could kill tumor cells and restrain inflammation to some extent. |
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| Keywords: | astragali tumor TNF-α IL-8 mice zoopery |
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