颅骨修补术后感染的相关因素分析

颅骨缺损为神经外科去骨瓣减压术常见的后遗症，多继发于重型颅脑损伤、高血压脑出血、颅内动脉瘤破裂大量出血、大面积脑梗死等需行开颅及去骨瓣减压术术后。为促进患者康复，一般于去骨瓣减压术后数周或数月内行颅骨修补。然而，如修补术后继发感染、或者采用钛网修补出现钛网外露等情况，即宣告该类手术失败，为患者带来更大的痛苦及额外的家庭经济负担。本文对颅骨修补术后感染的相关因素进行分析，并对如何预防术后感染进行讨论。

Analysis of the related factors affecting graft infection after cranioplasty

Skull defect, one of the most common sequela in neurosurgery, mainly results from severe trau-matic brain injury,hypertensive intracerebral hemorrhage, ruptured intracranial aneurysm and massive brain infarc-tion.Cranioplasty,which is helpful for the recovery of patients, is most commonly performed some weeks or months after the procedure.However,a failed procedure,such as secondary infection,titanium mesh exposure would lead to more pain for patients and additional financial burden to the family. The purpose of this review is to summarize the reasons and the corresponding preventive steps of cranioplasty infection on the basis of extensive literatures.