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恶性肿瘤合并抗利尿激素分泌异常综合征13例临床分析
引用本文:张红宇,吴昌平,周文杰,王琦. 恶性肿瘤合并抗利尿激素分泌异常综合征13例临床分析[J]. 江苏医药, 2011, 37(12)
作者姓名:张红宇  吴昌平  周文杰  王琦
作者单位:苏州大学附属第三医院(常州市第一人民医院)肿瘤内科,常州市,213003
摘    要:目的 分析合并抗利尿激素分泌异常综合征(SIADH)的恶性肿瘤患者的临床及实验室检查特点.方法 回顾性分析13例对ADH患者的原发肿瘤、临床特点、诊断及治疗情况.13例SIADH患者,基础疾病均为恶性肿瘤.患者无特殊临床症状,低钠血症的相关临床症状主要为倦怠、乏力、纳差、恶心、淡漠和头昏.结果 经限制液体摄入和补充氯化钠后,12例患者血钠水平恢复正常,5例小细胞肺癌化疗有效.结论 并发SIADH的肿瘤患者预后较差,应尽早诊断,必须限制液体入量和有效控制肿瘤.

关 键 词:抗利尿激素分泌异常综合征

Clinical analysis on the syndrome of inappropriate antidiuretic hormone secretion in patients with malignant tumor
ZHANG Hongyu,WU Changping,ZHOU Wenjie,et al.. Clinical analysis on the syndrome of inappropriate antidiuretic hormone secretion in patients with malignant tumor[J]. Jiangsu Medical Journal, 2011, 37(12)
Authors:ZHANG Hongyu  WU Changping  ZHOU Wenjie  et al.
Affiliation:ZHANG Hongyu,WU Changping,ZHOU Wenjie,et al.Department of Oncology,Affiliated Third Hospital,Soochow University,Changzhou 213003,CHINA
Abstract:Objective To summarize the diagnosis and management of the patients with the syndrome of inappropriate antidiuretic hormone secretion(SIADH).Methods The underlying tumor,clinical and laboratory characteristics,diagnosis and management of 13 cases were reviewed retrospectively.The underlying diseases were malignant tumors.The patients had no special clinical symptoms but were with hyponatremia-associated clinical symptoms of lassitude,asthenia,anorexia,nausea,apathy and dizziness.Results After water restrict...
Keywords:Syndrome of inappropriate antidiuretic hormone secretion  
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