丹赤饮治疗子宫内膜异位症临床研究

目的探讨丹赤饮治疗子宫内膜异位症的作用机理。方法42例子宫内膜异位症患者采用自身对照法,观察用药前后患者临床症状、体征的改善情况,及外周血NK细胞活性、抗子宫内膜抗体(EMAb)、血液流变学等变化情况。结果治疗后患者外周血NK细胞活性升高(P<0.01),EMAb阳性率降低(P<0.05),并能减轻患者血液高凝状态,临床总有效率90.48%。结论丹赤饮能纠正患者的免疫失衡及血瘀状态,能有效地改善临床症状和体征,无明显不良反应。

Clinical Study on Danchiyin in Treating Endometriosis

Objective To explore the therapeutic mechanism of endometriosis (EM) by the treatment of Danchiyin. Methods Forty-two cases with endometriosis were taken in control by themselves, to observe clinical symptoms and signs of patients with endometriosis before and after treatment. The activity of natural killer cell, EMAb and stream of peripheral blood were determined. Results After treatment, the activity of natural killer cell of peripheral blood were significantly increased (P <0.01), the rate of EMAb positive were decreased (P <0.05). Danchiyin could lighten the blood stasis of the patients with EM. The effective rate of the therapy was 90.48%. Conclusion Danchiyin could modulate the immunology disturbance and blood stasis in patients with EM, improve the clinical symptoms and signs obviously, without side effects.