利膈散联合顺铂方案治疗食管癌效果及对患者炎性因子、生活质量和不良反应的影响

目的:研究利膈散联合顺铂方案对食管癌患者效果及对炎性因子、生活质量和不良反应的影响。方法:选取83例食管癌患者纳入本次研究,以随机法将全部患者分为观察组(42例)与对照组(41例),对照组给予顺铂方案治疗,观察组给予利膈散联合顺铂方案治疗,观察两组患者治疗效果及对炎性因子、生活质量和不良反应的影响。结果:对照组总有效率为65.85%,观察组总有效率为71.43%,与对照组相比,观察组疗效更为优异(P<0.05);治疗后两组患者生活质量有所提高,不良反应、炎性水平显著降低,组内对比差异有统计学意义(P<0.05),而观察组改善程度均优于对照组,组间对比差异有统计学意义(P<0.05)。结论:利膈散联合顺铂方案对食管癌疗效确切,且对食管癌炎性因子、生存质量和不良反应具有较好的改善程度,值得临床应用。

Effect of Ligesan combined with cisplatin regimen on esophageal cancer patients and its effects on inflammatory factors,quality of life and adverse reactions

Objective:To study the effects of Ligesan combined with cisplatin on esophageal cancer patients and their effects on inflammatory factors,quality of life and adverse reactions.Methods:Eighty-three patients with esophageal cancer were randomly divided into observation group(42cases)and control group(41cases).The control group was treated with cisplatin regimen.The cisplatin regimen was used to observe the therapeutic effects of the two groups and their effects on inflammatory factors,quality of life and adverse reactions.Results:The total effective rate of the control group was 65.85%,and the total effective rate of the observation group was 71.43%.Compared with the control group,the observation group was more effective(P<0.05).After treatment,the inflammatory factors,quality of life and poorness of the two groups were improved.The response was improved,and the difference in the group was statistically significant(P<0.05),while the improvement of the observation group was better than that of the control group.The difference between the groups was statistically significant(P<0.05).Conclusion:Ligesan combined with cisplatin has a good effect on esophageal cancer,and it has a good improvement on inflammatory factors,quality of life and adverse reactions of esophageal cancer,which is worthy of clinical promotion.