| 胃食管反流病食管乳头内毛细血管环的形态学研究 |
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| 引用本文： | 吴建维,赖四海,林丽嫚,汤红玲.胃食管反流病食管乳头内毛细血管环的形态学研究[J].中国内镜杂志,2010,16(6). |
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| 作者姓名： | 吴建维 赖四海 林丽嫚 汤红玲 |
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| 作者单位： | 南方医科大学附属宝安医院消化内科,广东,深圳,518101 |
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| 摘 要： | 目的 探讨胃食管反流病(GERD)患者食管下段乳头内毛细血管环(IPCL)形态模式在GERD诊断中的应用价值.方法 对非糜烂性食管炎(NERD)患者20例、糜烂性食管炎(EE)患者20例和10名健康志愿者在白光和NBI模式下观察食管下段黏膜,再应用NBI模式放大内镜观察食管下段黏膜IPCL形态并进行分型.结果 NERD组患者24 h食管pH监测阳性率为55%,EE组为95%,NERD组显著低于EE组,健康对照组均为阴性;放大内镜NBI模式下健康对照组食管PCL呈茶色规律排列的卷发状、小螺旋状.NERD组85%及EE组100%食管IPCL形态为Ⅱ型,但仍排列规律,与健康对照组比较差异有显著性(P<0.05).结论 食管ICPL形态特异性改变有助于GERD的内镜诊断.
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| 关 键 词： | 胃食管反流病 非糜烂性食管炎 放大内镜 食管乳头内毛细血管环 |
Morphology of IPCL in gastroesophageal reflux disease |
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| WU Jian-wei
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LAI Si-hai
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LIN Li-man
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TANG Hong-ling.Morphology of IPCL in gastroesophageal reflux disease[J].China Journal of Endoscopy,2010,16(6). |
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| Authors: | WU Jian-wei LAI Si-hai LIN Li-man TANG Hong-ling |
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| Institution: | WU Jian-wei,LAI Si-hai,LIN Li-man,TANG Hong-ling (Departmant of Gastroenterology,Bao'an Hospital,Nanfang Medical University,Shenzhen,Guangdong 518101,P.R.China) |
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| Abstract: | Objective]To observe the morphology changes of IPCL in gastroesophageal reflux disease (GERD), and to explore its main magnified endoscopic characteristics. Methods]Forty out-patients with GERD, 20 NERD and 20 erosive esophagi (EE), were enrolled in this study, 10 healthy volunteers served as control. All the subjects were assessed with 24 hour ambulatory esophageal pH monitoring and magnifying endoscope. Biopsy specimens were taken from the region above the mucosa of the esophagogastric junction. Result... |
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| Keywords: | gastroesophageal reflux nonerosive reflux disease erosive esophagitis intra-epithelial papillary capillary loop |
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