| 阳江地区8867例妊娠妇女地中海贫血筛查结果分析 |
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| 引用本文： | 司徒桂花,司徒尤发,邝小玲. 阳江地区8867例妊娠妇女地中海贫血筛查结果分析[J]. 现代医院, 2011, 11(8): 154-156. DOI: 10.3969/j.issn.1671-332X.2011.08.076 |
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| 作者姓名： | 司徒桂花 司徒尤发 邝小玲 |
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| 作者单位： | 阳江市妇幼保健院,广东阳江,529500 |
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| 摘 要： | 目的开展妊娠妇女地中海贫血(以下简称地贫)筛查项目,了解本地区地贫的发病情况,降低重度地贫儿出生率,提高出生人口素质。方法对本院2008年7月～2010年12月产前门诊共8 867例孕妇进行血常规五分类检测,对怀疑地贫者进行地贫PCR基因分析,夫妇双方同为α-地贫或β-地贫携带者建议做产前诊断。结果筛查出地贫携带者1 049例,检出率为11.83%。其中α-地贫携带者842例,检出率为9.49%;β-地贫携带者203例,检出率为2.28%;α-地贫复合β-地贫者4例,检出率为0.04%。有173例孕妇接受产前诊断,检测出重型地贫儿24例。结论阳江地区是地贫高发区,通过对本地区妊娠妇女进行产前筛查与产前诊断,对重度地贫儿及早发现、及时引产,有效降低重度地贫儿出生率,对提高出生人口素质有重要意义。
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| 关 键 词： | 地中海贫血 产前筛查 重度地贫儿出生率 |
ANALYSIS OF THE OUTCOMES OF THALASSEMIA SCREENING IN 8 867 PREGNANT WOMEN OF YANGJIANG REGION |
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| SITU Guihua,SITU Youfa,KUANG Xiaoling. ANALYSIS OF THE OUTCOMES OF THALASSEMIA SCREENING IN 8 867 PREGNANT WOMEN OF YANGJIANG REGION[J]. Modern Hospital, 2011, 11(8): 154-156. DOI: 10.3969/j.issn.1671-332X.2011.08.076 |
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| Authors: | SITU Guihua SITU Youfa KUANG Xiaoling |
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| Affiliation: | SITU Guihua,SITU Youfa,KUANG Xiaoling Women and Children Healthcare Hospital of Yangjiang Municipality,Yangjiang,Guangdong Province 529500 PRC |
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| Abstract: | Objective To observe the incidence of thalassemia by carrying out the antenatal screening test aimed to reduce the birth rate of severe thalassemia fetal,and improve the population quality.Methods 8867 pregnant women were retrospectively studied by Blood routine test,at the Antenatal clinic from June 2008 to December 2010.Those who were suspected to be thalassemia had further genetic analysis.If the couples coincide to be the same type of thalassemia,prenatal diagnosis should be recommended.Results Totally ... |
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| Keywords: | Thalassemia Prenatal screening The birth rate of severe thalassemia fetal |
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