| IHC与FISH检测乳腺癌HER2状态一致性的对比研究及其临床意义 |
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| 引用本文： | 邵飞飞,康丽花,刘敏,白晶,宋艳秋. IHC与FISH检测乳腺癌HER2状态一致性的对比研究及其临床意义[J]. 吉林大学学报(医学版), 2011, 37(2): 292-295 |
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| 作者姓名： | 邵飞飞 康丽花 刘敏 白晶 宋艳秋 |
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| 作者单位： | 吉林大学第一医院肿瘤中心,吉林,长春,130021;吉林大学第一医院肿瘤中心,吉林,长春,130021;吉林大学第一医院肿瘤中心,吉林,长春,130021;吉林大学第一医院肿瘤中心,吉林,长春,130021;吉林大学第一医院肿瘤中心,吉林,长春,130021 |
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| 摘 要： | 目的:对比研究免疫组织化学方法(IHC)检测乳腺癌HER2蛋白表达和荧光原位杂交技术(FISH)检测HER2基因状态的一致性,并评价其临床意义.方法:采用IHC法及FISH法分别检测77例乳腺癌患者术后石蜡包埋标本的HER2蛋白表达和HER2基因状态,并进行对比分析.结果:77例乳腺癌患者术后石蜡包埋标本用IHC检测H...
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| 关 键 词： | 乳腺肿瘤 HER2 基因 荧光原位杂交技术 免疫组织化学技术 |
| 收稿时间： | 2011-01-02 |
Comparison of immunohistoehemistry and fluorescence in situ hybridization for assessment of HER2 in breast cancer and its clinical significance |
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| SHAO Fei-fei,KANG Li-hua,LIU Min,BAI Jing,SONG Yan-qiu. Comparison of immunohistoehemistry and fluorescence in situ hybridization for assessment of HER2 in breast cancer and its clinical significance[J]. Journal of Jilin University: Med Ed, 2011, 37(2): 292-295 |
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| Authors: | SHAO Fei-fei KANG Li-hua LIU Min BAI Jing SONG Yan-qiu |
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| Affiliation: | Cancer Center of First Hospital,Jilin University,Changchun 130021,China |
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| Abstract: | Objective To investigate the conformity between the HER2 protein examined by immunohistochemistry(IHC) and the HER2 gene detected with fluorescence in situ hybridization(FISH) and evaluate the clinical significance.Methods IHC and FISH were used to detect the expression of HER2 protein and amplification of HER2 gene,respectively,in paraffin-embedded tissues from 77 patients with breast cancer,the conformity beteween the results obtainde by the IHC and FISH was studided.Results Among 77 cases of paraffin-emb... |
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| Keywords: | HER2 |
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