超声检查对高血压颈动脉粥样硬化的评价及血流动力学分析

 目的 探讨高频超声探头观察高血压患者颈动脉内-中膜厚度及斑块形成的诊断价值.方法 使用高频超声对68例高血压患者,观察其颈动脉内-中膜厚度及有无斑块形成的情况,并检查48例健康体检为对照组.根据颈动脉超声检测有无粥样硬化将研究对象分为研究阳性组,研究阴性组,对照阳性组,对照阴性组.结果 研究阳性组共42例,占研究组61.8%,研究阴性组26例,占研究组38.2%,对照组阳性组13例,占对照组27.1%,对照阴性组37例,占对照组72.9%.研究组颈动脉粥样硬化检出率明显高于对照组(P<0.01).结论 本组研究表明高血压患者颈动脉内径明显增宽,血流速度明显减低,导致最大剪切力明显低于正常对照组,内中膜厚度增加与颈动脉粥样硬块密切相关,高血压患者血流动力学的改变对动脉硬化的发生及进展起着重要作用.

Haemodynamic analysis and evaluation of ultrasound on carotid atherosclerosis in hypertensive patients

Objective To determine the diagnostic value of high-frequency ultrasound probe on thickness of intimamedia and plaque formation in carotid artery of hypertensive patients.Methods We recruited 68 patients with hypertension and investigated the thickness of intimamedia and plaque formation in their carotid artery by high-frequency ultrasound probe,and another 48 healthy subjects as controls.Participants were divided into positive research group,negative research group,positive control group,and negative control group by presence or absence of atherosclerosis.Results Carotid atherosclerosis was found in 42 cases(61.8%) of positive research group,26 cases(38.2%) of negative research group,13 cases(27.1%) of positive control group,and 37 cases(72.9%) of negative control group.The detection rate of carotid atherosclerosis in research group was remarkly higher than in control group(P<0.01).Conclusions In hypertensive patients,the widened inner diameter and lower blood flow rate of carotid artery result in the maximal shearing force obviously lower than that in control group.The increasing intimamedia thickness is associated greatly with carotid atherosclerosis.The haemodynamic change plays an important role in the development and progression of atherosclerosis in hypertensive patients.