Efficacy and long-term tuning parameters of vagus nerve stimulation in long-term treated depressive patients |
| |
| Affiliation: | 1. Department of Clinical Epidemiology & Biostatistics, McMaster University, 1280 Main St W, Hamilton, ON L8S 4L8, Canada;2. University Health Network, 550 University Ave, Toronto, ON M5G 2A2, Canada;3. Peterborough Regional Nephrology Associates, 239 Charlotte St, Peterborough, ON K9J 2V1, Canada;4. Primary Health Care Services of Peterborough, 150 King Street, Peterborough, ON K9J 2R9, Canada |
| |
| Abstract: | Vagus nerve stimulation (VNS) is a promising neurostimulation tool for the treatment of treatment-resistant depression. Here, we report the effects of positive remission rates and tuning parameters in a group of 18 (6 female, 12 male, mean age 54) long-term treated patients.Treatment varied between 3 and 200 months (mean 104.9 months). Mean stimulation intensity was 1.46 mA, ranging from 0.5 to 2.0 mA and high-frequency stimulation of 20–25 Hz (mean 23.61 Hz).The remission rates in our study population clearly indicate ongoing positive effects of VNS and highlight stimulation tunings between 0.5 and 2.0 mA and 20–25 Hz as best dosage for achieving remittance in long-term treatment of VNS. |
| |
| Keywords: | Vagus nerve stimulation Depression Neurostimulation |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
