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Moving beyond Table 1: A critical review of the literature addressing social determinants of health in chronic condition symptom cluster research
Authors:Susan C. Grayson  Sofie A. Patzak  Gabriela Dziewulski  Lingxue Shen  Caitlin Dreisbach  Maichou Lor  Alex Conway  Theresa A. Koleck
Affiliation:1. School of Nursing, University of Pittsburgh, Pittsburgh, Pennsylvania, USA;2. Data Science Institute, Columbia University, New York, New York, USA

School of Nursing, University of Rochester, Rochester, New York, USA;3. School of Nursing, University of Wisconsin-Madison, Madison, Wisconsin, USA

Abstract:Variability in the symptom experience in patients diagnosed with chronic conditions may be related to social determinants of health (SDoH). The purpose of this critical review was to (1) summarize the existing literature on SDoH and symptom clusters (i.e., multiple, co-occurring symptoms) in patients diagnosed with common chronic conditions, (2) evaluate current variables and measures used to represent SDoH, (3) identify gaps in the evidence base, and (4) provide recommendations for the incorporation of SDoH into future symptom cluster research. We identified 118 articles including information on SDoH in chronic condition symptom cluster research. Articles primarily focused on cancer populations. Few articles had the explicit purpose of investigating relationships between SDoH and symptom clusters, and the inclusion of SDoH was often limited to variables used to describe samples. Future studies should be designed to “move beyond Table 1” in their utilization of SDoH as variables and examine relationships between SDoH and symptom clusters. Attention should be paid to the appropriateness of measures being used to collect information on SDoH, and analysis methods that estimate causal connections between variables should be considered. Research regarding the relationship of SDoH with symptom clusters in patients with chronic conditions has the potential to reveal mechanisms of symptom disparities and guide changes to alleviate these disparities.
Keywords:cancer  chronic conditions  signs and symptoms  social determinants of health  symptom clusters
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