Interventional radiology in breast cancer |
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| Affiliation: | 1. School of Medicine, University of Queensland, Australia;2. Royal Brisbane and Women''s Hospital, Australia;3. University Statale, Milan, Italy;4. Chair of the Division of Interventional Radiology at the European Institute of Oncology, Milan, Italy;5. Interventional Radiology, King’s College London, London, UK;6. Guy’s and St Thomas’s Hospital, London, UK;1. Department of Stroke Neurology, Kohnan Hospital, Sendai, Japan;2. Division of Cardiology, Cardiovascular Center, Sendai Kousei Hospital, Sendai, Japan;1. Department of Medical, Surgical Sciences and Advanced Technologies "G. F. Ingrassia," Neurological Surgery, Policlinico "Rodolico-San Marco" University Hospital, University of Catania, Catania, Italy;2. Department of Biomedicine, Neurosciences and Advanced Diagnostics (BiND), Neurosurgical Unit, Surgical Neuro-oncology Section, University of Palermo, Palermo, Italy;1. School of Psychology, The University of Sydney, NSW, Australia;2. Centre for Medical Psychology and Evidence-based Decision-making (CeMPED), The University of Sydney, NSW, Australia;3. Specialist Oncology Services, Norwest Private Hospital, NSW, Australia;4. Nepean Cancer Care Centre, Sydney West Cancer Network, NSW, Australia;1. Department of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Im Neuenheimer Feld 110, 69120 Heidelberg, Germany;2. Translational Lung Research Center Heidelberg (TLRC), Member of the German Lung ResearchCenter (DZL), Im Neuenheimer Feld 430, 69120 Heidelberg, Germany;3. Latvijas Universitate, Faculty of Medicine, Riga, Latvia;1. Division of Functional and Diagnostic Imaging Research, Department of Radiology, Kobe University Graduate School of Medicine, Kobe, Japan;2. Advanced Biomedical Imaging Research Centre, Kobe University Graduate School of Medicine, Kobe, Japan;1. Institute for Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany;2. Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Center for Lung Research, Hannover, Germany;1. Department of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Im Neuenheimer Feld 110, 69120 Heidelberg, Germany;2. Translational Lung Research Center Heidelberg (TLRC), Member of the German Lung ResearchCenter (DZL), Im Neuenheimer Feld 430, 69120 Heidelberg, Germany |
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| Abstract: | Molecular profiling of metastatic disease may greatly influence the systemic therapy recommended by oncologists and chosen by patients, allowing treatment to be more targeted. Comprehensive care of patients with advanced breast cancer now includes percutaneous image-guided biopsy if this has the potential to influence systemic treatment [1]. Interventional radiologists can contribute significantly to the care of patients affected by breast cancer, in diagnostic and supportive procedures and importantly also in treatment. Interventional radiologists carry out image guided percutaneous biopsies not only of the primary tumour but also of metastases. They insert percutaneous ports and tunnelled central venous catheters. They ablate painful bone metastases, and can treat or prevent pathological fractures. Most importantly they can ablate liver metastases in patients with limited or oligometastatic disease. The inhomogeneity and variety of cell populations in metastatic tumours from breast cancer, which is an important consideration in systemic therapy, is not an important consideration in the treatment of metastatic tumours using percutaneous ablative techniques, which are the major focus of this article. The treatment of primary tumours in the breast is also being explored, but is considered in its infancy at this stage. |
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| Keywords: | Interventional radiology Breast cancer Metastases |
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