Anxiety,depression and quality of life in patients with a treated or untreated unruptured intracranial aneurysm |
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| Institution: | 1. Department of Neurosurgery, Quzhou People’s Hospital, Quzhou, China;2. Department of Neurosurgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China;1. Department of Neurosurgery, Helsinki University Central Hospital, Helsinki, Finland;2. Neurosurgical Unit, EsSalud La Libertad, Trujillo, Peru;3. Department of Neurosurgery, Umberto I General Hospital, Università Politecnica delle Marche, Ancona, Italy;1. Division of Neurosurgery, Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, 30 Ngan Shing St, Sha Tin, New Territories, Hong Kong;2. Division of Neurology, Prince of Wales Hospital, The Chinese University of Hong Kong, Sha Tin, New Territories, Hong Kong;3. School of Public Health and Primary Care, Prince of Wales Hospital, The Chinese University of Hong Kong, Sha Tin, New Territories, Hong Kong;4. Department of Diagnostic Radiology, Kwong Wah Hospital, Hong Kong;5. Department of Imaging and Interventional Radiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong;1. Department of Ophthalmology, Division of Neuro-ophthalmology, Helsinki University Central Hospital, Helsinki, Finland;2. Department of Neurosurgery, Helsinki University Central Hospital, Helsinki, Finland;1. Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA;2. Vanderbilt University School of Medicine, Nashville, Tennessee, USA;1. Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada;2. Institute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada;3. MD/PhD Program, University of Toronto, Toronto, Ontario, Canada;4. Division of Neurosurgery, St. Michael''s Hospital, Labatt Family Centre of Excellence in Brain Injury and Trauma Research, Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, Toronto, Ontario, Canada;5. Division of Neurology, Department of Medicine, St. Michael''s Hospital, University of Toronto, Toronto, Ontario, Canada |
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| Abstract: | Living with an untreated unruptured intracranial aneurysm(UIA) is stressful, this study was aimed to assess the influence of UIA treatment (surgery clipping and endovascular coiling) on behavior such as anxiety and depression, as well as QoL. A series of 296 UIA patients (including 162 treated and 134 untreated) were analyzed. Postal questionnaires were sent to these patients, included Self-Rating Anxiety Scale (SAS), Self-Rating Depression Scale(SDS) and Short Form-36(SF-36). In total, 198 (66.9%) patients responded to our questionnaires. Patients with surgical clipping or endovascular coiling had a significant improvement in the physical function, body pain and mental health domains. No significant difference in the SAS, SDS and SF-36 was observed between the clipping and coiling group, while SF-36 in body pain domain was significant higher in the coiling group. Moreover, patients diagnosed 5 years ago with or without treatment got lower score of SAS and SDS, higher SF-36 score than those diagnosed one year ago. Neurological complications may be an important factor causing lower quality of life. The QoL of patients with endovascular coiling appear to be better than those of surgical clipping, with no difference in anxiety or depression. |
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| Keywords: | Anxiety Depression Quality of life Unruptured intracranial aneurysm |
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