An unusual presentation of varicella zoster virus with acute cerebellitis and SIADH without a rash |
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| Affiliation: | 1. Department of Neurology, St Vincent’s Hospital, 390 Victoria St, Darlinghurst, NSW, 2010 Sydney, Australia;2. The University of Notre Dame Australia, School of Medicine, Sydney, 160 Oxford St, Darlinghurst, NSW, 2010 Sydney, Australia;3. University of New South Wales, School of Medicine, Sydney, NSW 2052, Australia;1. School of Clinical Medicine, University of Cambridge, Cambridge, UK;2. Department of Medicine, Addenbrooke’s Hospital, Cambridge, UK;3. Department of Stroke Medicine, Queen Elizabeth Hospital, King’s Lynn, UK;4. Department of Clinical Neurosciences, Addenbrooke’s Hospital, University of Cambridge, Cambridge, UK;1. Gastroenterology Motility Research and Training, Texas Tech University Health Sciences Center El Paso, El Paso, TX, United States;2. Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center El Paso, El Paso, TX, United States |
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| Abstract: | We report a case of varicella-zoster virus (VZV) infection with acute cerebellitis and encephalitis with associated Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) in an elderly man presenting with acute cerebellar ataxia without antecedent rash. Cerebrospinal fluid examination (CSF) revealed a mononuclear pleocytosis, high protein, normal glucose, positive for VZV polymerase chain reaction (PCR). Early acyclovir treatment is beneficial for acute VZV cerebellitis. Clinicians should consider infectious Central Nervous System (CNS) causes for presentations of acute cerebellar ataxia in adult patients, particularly if there is an accompanying clouded sensorium. |
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| Keywords: | Acute cerebellitis Varicella zoster virus Encephalitis SIADH Acute ataxia |
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