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Point/counterpoint: We should not take the direction of blood pressure change into consideration for dynamic cerebral autoregulation quantification
Authors:Kyriaki Kostoglou  David M Simpson  Stephen J Payne
Affiliation:1.Institute of Neural Engineering, Graz University of Technology, Graz, Austria; 2.ISVR, Faculty of Engineering and the Environment, University of Southampton, Southampton, UK; 3.Institute of Applied Mechanics, National Taiwan University, Taipei
Abstract:Over the past years, a wide range of studies have provided evidence of asymmetry in the response of static and dynamic cerebral autoregulation (CA) during increasing and decreasing pressure challenges. The main message is that CA is stronger during transient increases of arterial blood pressure rather than decreases. Here we do not argue against the presence of CA asymmetry but we seek to raise questions regarding the measurement of the effect and whether this effect needs to be taken into account, especially in clinical settings.
Keywords:Asymmetry   cerebral autoregulation   cerebral blood flow   cerebral haemodynamics   transcranial Doppler
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