天然滨珊瑚无害化处理后形态学和抗压强度的变化

目的：检测天然滨珊瑚经化学和物理方法处理后大体结构、显微结构以及抗压强度等变化。方法：用牙科电机将天然滨珊瑚制备成6mm×8mm×10mm的类椭圆形方块，放入5％次氯酸钠溶液中浸泡2周，煮沸3个周期、超声清洗5个周期，然后烤干，高温高压消毒。检测珊瑚处理前、处理后和消毒后的抗压强度变化，体视显微镜和扫描电镜下观察珊瑚表面和孔隙清洁度及大小变化。结果：3个观察时段珊瑚的抗压强度无明显变化，分别为（7．07-0．32）MPa，（7．25±0．24）MPa，（7．25±0．13）MPa。经浸泡和超声处理后珊瑚表面和孔隙内明显清洁，异物减少，孔隙大小和结构无明显改变。高温高压消毒后珊瑚表面和孔隙与处理后组一致。结论：天然滨珊瑚经物理、化学处理后表面和内部异物被清除，外观结构和抗压强度不受影响，可以作为选择骨缺损修复材料或骨组织工程支架材料时的参考依据。

Changes of general morphology and compressive strength after natural porites harmless treatment.

Objective：To test the changes of natural porites general morphology,microstructure and compressive strength after their chemical and physical treatment. Method： The porties were made into oval shape blocks （6 mm × 8 mm×10 mm）, and immersed in 5% sodium hypochlorite solution for 2 weeks, the solution was replaced once every three days： then boiled three times with 10 rain in each time; and followed by uhrasonication for five times with 10 min in each time. At last, they were dried in the oven （80 ℃, 24 h） and sterilized under condition of high temperature and high pressure （1.3 MPa, 131 ℃ ,30min）. Evaluation methods included testing the changes of their general morphology, microstructure and compressive strength during the three stages. Result： There was no great change of compressive strength in different stages （7.07±0.32） MPa, （7.25±0.24）MPa, （7.25±0.13）MPa. After the porites were treated by chemical and physical methods,as well as by sterilization,most of foreign bodies were cleared. The surfaces and interspaces of porites became clean and smooth. Conclusion： The foreign bodies of porites surfaces and interspaces could be cleared by chemical and physical methods. There were no great changes about structure and compressive strength during the treatment.