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布地奈德雾化吸入对悬雍垂腭咽成形术后咽部水肿及疼痛的作用
引用本文:梅金玉,杨见明,王媛媛,曹卫,王雅堂. 布地奈德雾化吸入对悬雍垂腭咽成形术后咽部水肿及疼痛的作用[J]. 安徽医药, 2010, 14(12): 1477-1478. DOI: 10.3969/j.issn.1009-6469.2010.12.052
作者姓名:梅金玉  杨见明  王媛媛  曹卫  王雅堂
作者单位:安徽医科大学第二附属医院耳鼻咽喉-头颈外科,安徽,合肥,230601;安徽医科大学第二附属医院药剂科,安徽,合肥,230601
摘    要:目的探讨悬雍垂腭咽成形术后应用布地奈德雾化吸入对咽部粘膜水肿及疼痛的影响。方法对52例阻塞性睡眠呼吸暂停低通气综合征患者行悬雍垂腭咽成形术,随机分为治疗组和对照组,治疗组术后1~6 d应用布地奈德雾化吸入,观察患者咽部水肿及疼痛情况并与对照组进行对比。结果治疗组患者咽部水肿消失在(4.23±0.71)d;对照组患者咽部水肿消失在(5.38±0.70)d;两组差异有显著性。治疗组患者咽部疼痛评分第2天开始较对照组差异有显著性。结论悬雍垂腭咽成形术后患者应用布地奈德雾化吸入可有效减少咽部粘膜水肿及疼痛,值得临床推广。

关 键 词:阻塞性睡眠呼吸暂停低通气综合征  悬雍垂腭咽成形术  布地奈德

Effect of inhaling budesonide on pain and edema for patients after UPPP
MEI Jin-yu,YANG Jian-ming,WANG Yuan-yuan,CAO Wei,WANG Ya-tang. Effect of inhaling budesonide on pain and edema for patients after UPPP[J]. Anhui Medical and Pharmaceutical Journal, 2010, 14(12): 1477-1478. DOI: 10.3969/j.issn.1009-6469.2010.12.052
Authors:MEI Jin-yu  YANG Jian-ming  WANG Yuan-yuan  CAO Wei  WANG Ya-tang
Affiliation:MEI Jin-yu1,YANG Jian-ming1,WANG Yuan-yuan2,CAO Wei1,WANG Ya-tang1(1.Dept of Otorhinolaryngology Head and Neck Surgery,2.Dept of Pharmacy,The Second Affiliated Hospital of Anhui Medical Univesity,Hefei,Anhui 230601,China)
Abstract:Aim To observe the influence of postoperative continuous application of budesonide inhalation aerosol on pain and edema for patients after uvulopalatopharyngoplasty(UPPP).Methods Fifty-two patients after UPPP were randomly divided into the treatment group and the control group.Budesonide inhalation aerosol was adopted in the treatment group at 1~6 days after operation and routine treatment was conducted in the control group.The decrease of pain and edema was observed for patients after UPPP.Results The average disappearence of edema for the treatment group patients was 4.23 ± 0.71 days,and for the control group patients was 5.38 ± 0.70 days It has a significant difference in statistics(p < 0.001).The difference in pain relief was significant between the two groups.In the treatment group,pain degree after UPPP was obviously decreased from the second day,and the relief effect better than that in the control group.Conclusion The budesonide inhalation aerosol for patients after UPPP could obviously relieve pain and edema,which should be recommended generally by clinic.
Keywords:uvulopalatopharyngoplasty  obstructive sleep apnea hypopnea syndrome  budesonide  
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