| 蜂胶的药理作用研究 |
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| 引用本文： | 栾金水,王南舟,田路. 蜂胶的药理作用研究[J]. 中药材, 2000, 23(6): 346-348 |
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| 作者姓名： | 栾金水 王南舟 田路 |
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| 作者单位： | 1. 杭州商学院食品科学与工程系,310035
2. 杭州市第一人民医院,310012 |
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| 基金项目： | 本文为浙江省科委"蜂胶的功能性应用开发"课题部分研究内容,编号991102188. |
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| 摘 要： | 蜂胶药理作用的研究结果显示：对小鼠有抗疲劳耐缺氧作用,能阻止高脂血症模型大鼠血粘度和血脂（ＴＣ、ＴＧ、ＬＤＬ－Ｃ）升高（Ｐ〈０．０５～０．０１）,但红血球比积（Ｈｃｔ）和高密度脂蛋白胆固醇（ＨＤＬ－Ｃ）改变不显著;能增强免疫抑制模型小鼠腹腔巨噬细胞吞噬功能（Ｐ〈０．０５）,增强胸腺指数（Ｐ〈０．０５）,但脾指数改变不明显。给小鼠灌服蜂胶ＬＤ５０〉７５００ｍｇ／ｋｇ。
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| 关 键 词： | 蜂胶 巨噬细胞 抗应激作用 抗疲劳 药理作用 |
| 修稿时间： | 2000-01-03 |
Study on the Pharmacologic Effect of Propolis |
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| Luan Jinshui,Wang Nanzhou,Tian Lu. Study on the Pharmacologic Effect of Propolis[J]. Journal of Chinese medicinal materials, 2000, 23(6): 346-348 |
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| Authors: | Luan Jinshui Wang Nanzhou Tian Lu |
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| Affiliation: | Department of Food Science and Engineering, Hangzhou University of Commerce, Hangzhou 310035. |
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| Abstract: | Pharmacologic effects of propolis were investigated in this article.The results suggested that propolis has pharma-cologic functions in many aspects.It is a new-type medicine derived from animal in pharmacology and food both.To small mouse, propolis showed the functions of anti-fatigue and endurance to lack of oxygen.To high-blood-lipid-model mouse, it prevented increase of blood-mucus and blood lipid(TC,TG,LDL-C) (P<0.05-0.01),but there were insignificant changes to red-blood-cell proportion (HCT) and high-density lipoprotein chelesteral (HDC-C) .To small immunosuppessive-model mouse, propolis could strengthen macrophagocyte phagocytosis in the abdominal-cavity (P<0.05),and increase the thymus-index (P < 0.05), but there were insignificant changes to the spleen-index.The LD50 > 7500 mg/kg to small mouse. |
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| Keywords: | Propolis Blood mucus Blood lipid Macrophagoxyte phagocytosis Anti-exitability Flavonoides |
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