Failure of antiserotonergic agents to modify levallorphan-induced stereotypy in rats |
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Authors: | Keith C. Phillips Samuel R. Wray |
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Affiliation: | (1) Laboratoire de Psychophysiologie, Université Louis Pasteur, Strasbourg, France |
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Abstract: | n-Dipropylacetate (nDPA), at a dose of 100 mg/kg, has a facilitating action on the acquisition of conditioned reactions with negative reinforcement in mice. On the other hand, nDPA reduces the number of conditioned reactions with a dose of 200 mg/kg. These effects of nDPA on conditioned behaviour are correlated with the increase of the level of brain gamma-aminobutyric acid, following administration of nDPA. |
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Keywords: | n-Dipropylacetate Operant behaviour Brain gamma-aminobutyric acid Avoidance |
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