LIVER TRANSPLANTATION FOR HEPATIC CANCER

ＬＩＶＥＲＴＲＡＮＳＰＬＡＮＴＡＴＩＯＮＦＯＲＨＥＰＡＴＩＣＣＡＮＣＥＲＸｉａＳｕｉｓｈｅｎｇ夏穗生（ＩｎｓｔｉｔｕｔｅｏｆＯｒｇａｎＴｒａｎｓｐｌａｎｔａｔｉｏｎ，ＴｏｎｇｊｉＭｅｄｉｃａｌＵｎｉｖｅｒｓｉｔｙ，Ｗｕｈａｎ４３００３０）Ａｂｓｔｒａ...

Liver transplantation for hepatic cancer

Controversy still exists in the liver transplantation as one of the surgical treatments for hepatic cancer. Of the 14 cases of orthotopic liver transplantation performed in our institute since 1977, 12 cases were primary liver cancer (PLC). No intraoperative and immediate postoperative death occured. Four cases survived for over 3 months, in whom 2 survived for over half a year, and 1 nearly 9 months. The main causes of death were liver failure, rejection, tumor recurrence and infection. The results and the indication of liver transplantation for PLC are discussed. The liver cancer classification more suitable for PLC and selection of the surgical treatment are suggested. It is hold that the liver transplantation is justified for the PLC at stage I, type B and stage I. The reasons why the results of the liver transplantation were poor in China and in our institute are analyzed. It is believed that better results will be gained by means of more strict case selection, immprovement of surgical technique and Cyclosporin A (CsA) application.