胃肠管间质瘤23例临床诊治分析

目的 探讨胃肠管间质瘤的诊断和治疗.方法 对2000年7月～2005年10月外科治疗的胃肠管间质瘤病例进行回顾性分析.结果 23例均行手术治疗,其中手术切除21例,未行手术切除2例.病理诊断良性7例,潜在恶性6例,恶性10例.随访时间10个月至6年,3例出现远处转移或局部复发,5例死亡.结论 胃肠管间质瘤术前确诊率低,超声内镜和影像学检查是发现胃肠管间质瘤病变的主要手段,其确诊依赖病理结果,手术切除是治疗的主要方法.

Diagnosis and treatment of gastrointestinal stromal tumor: an analysis of 23 cases

Objective To evaluate the clinical diagnosis and treatment of gastrointestinal stromal tumors (GISTs). Methods The clinical data of patients with GISTs admitted into surgical department from July 2000 to Oct 2005 were retrospectively analyzed. Rusults Twenty-three patients received operation. Twenty-one patients underwent complete tumor resection, two did laparotomy only. Among the patients 7 cases were benign ,6 potential malignant, and 10 malignant . All patients were followed-up from 10 to 72 months. Three of the patients had local recurrence and metastasis, and 5 patients died. Conclusion It was difficult the diagnosis of GISTs because of the lack of clinical feature. Endoscopy and imaging examination are main methods to detect GISTs. Final diagnosis should be based on pathology. Surgical rection is the main treatment.