| 重症肝炎Glucagon-Insulin疗法滴注前后血中胰岛素、胰升血糖素等浓度变化 |
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| 引用本文： | 孟令先,刘沛,董祥家,李彦卿,金玉珠.重症肝炎Glucagon-Insulin疗法滴注前后血中胰岛素、胰升血糖素等浓度变化[J].中国医科大学学报,1988(3). |
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| 作者姓名： | 孟令先 刘沛 董祥家 李彦卿 金玉珠 |
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| 作者单位： | 中国医科大学附属第三医院肝炎研究室
(孟令先，刘沛，董祥家)，沈阳市传染病院
(李彦卿)，沈阳市传染病院(金玉珠) |
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| 摘 要： | 经肝活检证实的重症肝炎11例,在胰高血糖素-胰岛素(G-I)疗法前及滴完后15、30、60、120、180分钟采血,检测血清糖、胰岛素、C肽及血浆胰升血糖素。结果:血糖在滴注前正常或偏低,滴后轻度上升即降至滴前水平;胰岛素、C肽及胰升血糖素滴前均高于正常,滴后15分钟高峰,滴后3小时C肽及胰升血糖素恢复到滴前水平,而胰岛素持续呈高值。可见重症肝炎对胰岛素的摄取和降解功能降低,而对胰升血糖素有摄取和降解功能。
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| 关 键 词： | 胰高血糖素-胰岛素疗法 胰岛素 C肽 胰升血糖素 |
CHANGES OF BLOOD CONCENTRATION OF INSULIN AND GLUCAGON IN FULMINANT HEPATITIS BEFORE AND AFTER GLUCAGON-INSULIN TREATMENT |
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| Meng Lingxian,et al.CHANGES OF BLOOD CONCENTRATION OF INSULIN AND GLUCAGON IN FULMINANT HEPATITIS BEFORE AND AFTER GLUCAGON-INSULIN TREATMENT[J].Journal of China Medical University,1988(3). |
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| Authors: | Meng Lingxian |
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| Institution: | The Third Affiliated Hospital |
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| Abstract: | Blood sugar, insulin and C-peptide were detected in 11 cases of fulminant heratitis confirmed by liver biopsy before G-I treatment and 15, 30, 90, 120, 180 minutes after instillation.The restults showed that blood sugars were normal or less before instillation, ard elevated slightly then dropped to normal level afler instillation.Insulin C-peptide and glucagon were bigger than normal before instillation and reached peak value 15 minutes after instillation,C-peptide and glucagon recovered to pre-instillation level 3 hours after instilla tion. But insulin persisted in peak value. Therefore in the patients with fulminant hepatitis,function to intake and to degrade insulin decreased, and the function to intake and to degrade glucagon was present. |
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| Keywords: | Insulin Glucagon C-peptide Glucagon-insulin treatment |
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