超声弹性成像监测冷冻手术的仿真实验研究

从生物组织冻结前后其弹性模量会发生显著改变的角度出发,在提出了低温外科手术中监测冰球形成与消融过程的超声弹性成像方法的研究基础上,设计了3类概念性超声弹性监测试验：含玻璃体模、常温组织体模及冻结组织体模仿真试验,首次从实验上证实了超声弹性成像方法在低温外科手术中对冰球实施高对比度成像的可行性。文章分析了该方法在应用中的一些测量误差,指出了进一步改进的方向。冰球这种与水呈高弹性对比度的临床监测对象,可望成为超声弹性成像医学应用中的一个重要主题。

Simulating experimental study on ultrasonic elastography based monitoring of cryosurgery

Noticing the phenomenon that biological tissues will change its elasticity by orders of magnitude after it was frozen, we proposed in principle the strategy of using ultrasound elastography to monitor the formation and thawing of the iceball when performing a cryosurgery. Following our former theoretical evaluation, conceptual experiments were designed to apply ultrasound elastography to monitor three kinds of testing samples which includes: phantom embedded with glass block, phantom with tissues at normal temperature and phantom with frozen tissues inside. It was demonstrated for the first time that the ultrasound elastography could provide a high contrast picture on the ice ball during cryosurgery. The measurement errors involved in the application of the method was preliminarily analyzed and approaches to further improve the method were pointed out. With a much different value in elastography than that of water, monitoring the ice ball, the imaging target in clinics, is expected to be an important area for the application of ultrasound elastography.