| 非实验因素对人体核磁共振代谢组学检测结果的影响 |
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| 引用本文： | 吴巧凤,余曙光,颜贤忠.非实验因素对人体核磁共振代谢组学检测结果的影响[J].生物医学工程学杂志,2008,25(1):204-207. |
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| 作者姓名： | 吴巧凤 余曙光 颜贤忠 |
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| 作者单位： | 1. 成都中医药大学,针灸推拿学院,成都,610075
2. 军事医学科学院,国家分析测试中心,北京,100850 |
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| 基金项目： | 国家重点基础研究发展计划(973计划) |
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| 摘 要： | 代谢组学被认为是未来诊断疾病和评价患者机能状况的有力手段,但目前的研究结果表明,很多非实验因素,如饮食、运动、环境以及个体差异等均会影响临床实验结果,为保证不同核磁共振(Nuclear magnetic resonance,NMR)实验数据之间的可比性,很有必要在实验设计和数据分析过程中对这些因素进行合理的控制.
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| 关 键 词： | 代谢组学 核磁共振 饮食 运动 性别 环境 实验设计 因素 核磁共振 代谢组学 检测 结果 影响 Study Metabonomics Resonance Nuclear Human Factors 控制 过程 数据分析 可比 实验数据 magnetic resonance 临床实验 |
| 文章编号： | 1001-5515（2008）01-0204-04 |
| 收稿时间： | 2007-03-08 |
| 修稿时间： | 2007-09-12 |
The Effect of Non-Experimental Factors on Human Nuclear Magne tic Resonance Metabonomics Study |
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| Wu Qiaofeng,Yu Shuguang,Yan Xianzhong.The Effect of Non-Experimental Factors on Human Nuclear Magne tic Resonance Metabonomics Study[J].Journal of Biomedical Engineering,2008,25(1):204-207. |
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| Authors: | Wu Qiaofeng Yu Shuguang Yan Xianzhong |
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| Institution: | Acupuncture and Maxibustion College, Chengdu University of TCM, Chengdu 610075, China. |
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| Abstract: | Metabonomic approaches are believed to be one of the powerful methods for disease diagnosis and assessment of patients' conditions.However,many publications have been providing the evidences of the biases caused by many factors such as diet,physical exercises,environment and individual differences in the clinical researches.For the purpose of ensuring the comparability of metabonomic 1H NMR data from different studies,it is necessary to control those non-experimental factors in the study design and the data analysis. |
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| Keywords: | Metabonomics Nuclear magnetic resonance Diet Physical exercise Gender Environment |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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