职业性混苯暴露工人神经行为功能改变

利用世界卫生组织（ＷＨＯ）推荐的神经行为核心测试组合（ＮＣＴＢ）对１０３名职业性混苯暴露工人，以及７２名无职业性有害因素接触的同厂工人进行测试。结果发现：暴露组在情感状态（ＰＯＭＳ）、手工敏捷度、数字广度、数字译码、目标追踪等项目得分都低于对照组，其中优势手手工敏捷度、目标追踪两项得分差异具显著性。按车间混苯浓度分为高暴露组和低暴露组，多因素分析发现：高暴露组情感状态（ＰＯＭＳ）中的抑郁－沮丧和有力－好动、数字广度、手工敏捷度（优势手和非优势手）、数字译码、目标追踪等项显著低于对照组和低暴露组。提示混苯暴露使工人神经行为功能表现某些方面的改变，如心情趋于抑郁、缺乏活动性，短时记忆力、理解力、运动速度、协调性等方面表现较差。

Neurobehavioral Function of Workers Exposed Occupationally to Organic Solvent:Toluene,Xylene and Benzene

Neurobehavioral funtions of 103 workers (69 oil print makers and 34 shoes makers)exposed occupationally to mixed organic solvents were studied here.Solvents were composed mainly of toluene,xylene and benzene 72. workers without exposure of neurotoxic factors in the same factories were studied simultaneously as a control group.The Neurobehavioral Core Test Battery (NCTB) recommended by WHO was applied to investigate neurobehavioral functions of the studied population.Our results showed:compared with controls,the scores of the exposed workers of Profile Of Mood Staes(POMS),Santa Ana manual dexterity,digit span,digit symbol,pursuit aiming were lower,but only Santa Ana manual dexterity of dominant bands and pursuit aiming tests showed significant difference(P<0 05).According to concentrations of Solvent at workplaces,oil print workers were studied as lower exposure group,and shoe workers as higher exposure group.Compared with oil print workers and controls,the scores of shoe workers of depression and vigor of POMS,digit span,Santa Ana manual dexterity of both hands,digit symbol and pursuit aiming tests were statistically significantly lower.According to these findings,it can be concluded that mixed organic solvents of toluene,xylene and benzene,have harmful effects on neurobehavioral functions of exposed workers,such as feeling depressed,less vigor,lower motor speed,poor ability to correspond,shortly remember and understand.NCTB is a simple and sensitive method to find out these harmful effects,will be used widely in the future.