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| 小檗碱对2型糖尿病大鼠肾脏GLUT1表达的影响 | |
| 引用本文： | 王良君,杨亮,刘学政. 小檗碱对2型糖尿病大鼠肾脏GLUT1表达的影响[J]. 解剖学研究, 2011, 33(4): 248-251,封4 |
| 作者姓名： | 王良君 杨亮 刘学政 |
| 作者单位： | 1. 辽宁医学院公共卫生管理学院卫生学教研室,辽宁,锦州121000 2. 北京协和医院放射科,北京10005 3. 辽宁医学院基础学院人体解剖学教研室,辽宁,锦州121000 |
| 摘 要： | 目的 探讨小檗碱(Berberine,BBR)对2型糖尿病(type 2 diabetes mellitus,T2DM)大鼠肾脏葡萄糖转运蛋白1(glucose transporter protein 1,GLUT1)表达的影响及其对肾保护作用的机制,为临床用其防治糖尿病肾病打下理论基础.方法 45只健康雄性SD大鼠适... |
| 关 键 词： | 小檗碱 糖尿病大鼠,2型 葡萄糖转运蛋白1 |
The effect of berberine on the expression of glucose transporler 1 in the kidney of type 2 diabetes mellitus rats |
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| WANG Liang-jun,YANG Liang,LIU Xue-zheng. The effect of berberine on the expression of glucose transporler 1 in the kidney of type 2 diabetes mellitus rats[J]. Anatomy Research, 2011, 33(4): 248-251,封4 | |
| Authors: | WANG Liang-jun YANG Liang LIU Xue-zheng |
| Affiliation: | WANG Liang-jun,YANG Liang,LIU Xue-zheng.Department of Preventive Medicine,Management and Public Health Science College of Liaoning Medical University,Jinzhou 121000,China |
| Abstract: | Objectives To investigate the effect of berberine on the expression of GLUT1 in the kidney of type 2 diabetes mellitus rats,and the mechanism of the protective effect of berberine on kidney,which can be useful for the clinical application to prevent and cure diabetic nephropathy.Methods 45 healthy male SD rats were adaptively fed for one week,and then ten were randomly selected from them as the normal control group,which were given ordinary feed.The remaining rats were fed with high-lipoglucose food for two... |
| Keywords: | Berberine Diabetes meuitus rat type 2 Glucose transporter protein 1 |
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