| 甲状腺摄碘率对甲亢患者131I疗效影响的研究 |
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| 引用本文： | 马玉琴,梁华举,许跃玲. 甲状腺摄碘率对甲亢患者131I疗效影响的研究[J]. 中国辐射卫生, 2011, 0(1): 35-36 |
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| 作者姓名： | 马玉琴 梁华举 许跃玲 |
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| 作者单位： | 山东省地方病防治研究所山东省甲状腺疾病防治中心; |
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| 摘 要： | 目的通过回顾性研究甲状腺摄碘率（RAIU）与有效半衰期（EHL）对甲亢患者131I疗效的影响，探讨131I治疗甲亢的更有效方案。方法收集531例行131I治疗的Graves病患者资料，包括131I疗前的RAIU、EHL检查结果，及定期检测的F13、FT4、sTSH、TRAb等结果。根据RAIU高峰值、高峰时间、EHL不同分别进行分组，观察各组近期预后。结果RAIU高峰值越高，未愈比例越高。高峰值（100～91）％组痊愈比例最低，高峰值（70～51）％组甲减发生比例最高。高峰值出现的越早，未愈比例越高，甲减发生比例越低。EHL最长组痊愈比例最低，未愈比例最高；EHL小于4天组未愈比例也较高。结论RAIU高峰值高于90％或低于70％者，及高峰时间太短或EHL小于4d者，131I疗效较差，需调整131I治疗量。EHL长短与131I疗效不成正比，当EHL大于7d时，不宜因此而减少131I治疗用量。
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| 关 键 词： | 甲亢 甲状腺摄碘率 有效半衰期 131I治疗 预后 |
Investigation on the Impact of Rate of Thyroid Iodine Uptake on the Effect of ~(131)I Treatment of hyperthyroidism |
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| MA Yu-qin,LIANG Hua-ju,XU Yao-ling. Sh,ong Institute for Endemic Disease Control , Research,Jinan ,China. Investigation on the Impact of Rate of Thyroid Iodine Uptake on the Effect of ~(131)I Treatment of hyperthyroidism[J]. Chinese Journal of Radiological Health, 2011, 0(1): 35-36 |
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| Authors: | MA Yu-qin LIANG Hua-ju XU Yao-ling. Sh ong Institute for Endemic Disease Control Research Jinan China |
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| Affiliation: | MA Yu-qin,LIANG Hua-ju,XU Yao-ling. Shandong Institute for Endemic Disease Control and Research,Jinan 250014,China |
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| Abstract: | Objective Through retrospective study of rate of iodine uptake(RAIU) and effective half-life(EHL) effect on the impact of 131I therapy for hyperthyroidism,To Investigate a more effective program of 131I treatment of hyperthyroidism.Methods Data of 531 patients with hyperthyroidism after 131I treatment were collected,and including test results of RAIU and EHL before the 131I treatment,the serum FT3,FT4,sTSH,TRAb and so on before and after 131I treatment.To be grouped according to the difference of the peak v... |
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| Keywords: | Hyperthyroi Dism Rate of Thyroid Iodine Uptake Effective half-life 131I treatment Prognosis |
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