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八仙草化学成分研究
引用本文:李建,陈立,李彬,刘士军,董俊兴. 八仙草化学成分研究[J]. 国外医学(药学分册), 2010, 0(5): 387-389
作者姓名:李建  陈立  李彬  刘士军  董俊兴
作者单位:军事医学科学院放射与辐射医学研究所七室,北京100850
摘    要:目的研究八仙草(Galium aparineL.)全草的60%乙醇提取物的化学成分。方法采用硅胶柱色谱、Sephadex LH-20凝胶柱色谱及制备薄层等方法进行分离纯化,通过波谱解析和理化鉴别进行结构鉴定。结果分离鉴定了8个黄酮类化合物,分别为槲皮素(1),木犀草素(2),芹菜素(3),橙皮素(4),醉鱼草苷(5),山奈酚-3-新橙皮糖苷(6),柽柳素-3-芸香糖苷(7),橙皮苷(8)。结论化合物3~7首次从该植物中分离得到。

关 键 词:八仙草  化学成分  黄酮

Study on the chemical consitituents of Galium aparine L.
LI Jian,CHEN Li,LI Bin,LIU Shi-jun,DONG Jun-xing. Study on the chemical consitituents of Galium aparine L.[J]. Foreign Medical Sciences(Section of Pharmarcy), 2010, 0(5): 387-389
Authors:LI Jian  CHEN Li  LI Bin  LIU Shi-jun  DONG Jun-xing
Affiliation:(Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850, China)
Abstract:Objective To investigate the chemical constituents in 60% alcohol extract of Galium aparine L. Methods The compounds were isolated by column chromatography over silica gel and Sephadex LH-20 coupled with preparative silica gel TLC. Results Eight compounds were isolated from G. aparine L. which were identified as quercetin (1), luteolin (2), apigenin (3), hesperetin (4), linarin (5), kaempferol-3-neohesperidose (6), tamarixetin-3-rutinoside (7) and hesperidin (8). Conclusion Compounds 3-7 were isolated from this plant for the first time.
Keywords:Galium aparine  chemical consitituents  flavonoids
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