左氧氟沙星序贯治疗社区获得性肺炎的疗效观察

目的评价左氧氟沙星序贯治疗社区获得性肺炎的疗效。方法将96例社区获得性肺炎患者随机分为两组,治疗组49例,给予左氧氟沙星注射3d后改为口服;对照组47例,给予头孢呋辛钠联合阿奇霉素注射3d后改为口服。两组疗程均为7～14d。观察临床症状、体征、胸部X线和实验室检查等指标。结果两组临床疗效差异无显著性（P〉0.05）,不良反应差异无显著性。结论左氧氟沙星序贯治疗社区获得性肺炎疗效确切,值得推广。

Observation on therapeutic effect of sequential therapy with levofloxacin on community acquired pneumonia

Objective To evaluate the efficacy of sequential treatment of levofloxacin on community acquired pneumonia.Methods 96 patients with community acquired pneumonia were divided into levofloxacin group（49 patients）and control group（47 patients treated with Cefuroxime sodium plus azithromycin）,the drugs were given sequentially by intravenous infusion for 3 days,then changed to oral administration for 7 to 14 days.Their clinical symptoms,signs,chest X-ray examination and laboratory findings were observed and compared in these 2 groups.Results There was no significant difference in efficacy rate between these two groups;there were less adverse reactions in levofloxacin group.Conclusion Sequential therapy of levofloxacin for community acquired pneumonia was reliable.Levofloxacin may be offered as an alternative to clinicians for treatment of community acquired pneumonia.