腹部内脏脂肪厚度与冠状动脉狭窄关系的研究

目的探讨冠心病患者腹部内脏脂肪厚度(VFT)与冠状动脉狭窄的关系。方法选择2007年9月至2009年1月在广西医科大学第五临床医院行冠状动脉造影的216例患者,其中冠心病148例,记录身高、体重、腰围、血压等,检测血脂、空腹血糖、尿酸、肾功能等指标,对冠状动脉狭窄程度进行定量Gensi-ni积分,同时应用超声测量VFT,根据VFT值将患者分为低、中、高值3组。结果与低值组比较,中、高值组患者腰围、体重指数较大,高血压、糖尿病比例高(P<0.05),三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)明显增高,高密度脂蛋白胆固醇(HDL-C)显著降低。VFT与年龄、腰围、体质量指数、TG、LDL-C呈正相关,与HDL-C呈负相关。随着VFT值增加,Gensini积分明显增大。Logistic回归分析显示年龄、TG、低HDL-C、糖尿病和VFT是冠心病的独立危险因素,校正腰围后VFT的OR值有所减小,但差异仍有统计学意义。结论冠心病患者VFT与冠状动脉狭窄严重程度呈明显正相关,VFT测量可以作为冠心病患者危险评估的有用指标。

Relationship between visceral fat thickness and severity of coronary artery stenosis in patients with coronary artery disease

Objective To investigate the relationship between VFT and the severity of coronary artery stenosis(CAS)in patients with coronary artery disease.Methods 216 patients who were hospitalized to undergo coronary angiography entered the study,148 patients was diagnosed as coronary artery disease,record all patients height,weight,waist circumference,blood pressure and so on,subjects were detected blood lipids,fasting plasma glucose,uric acid,renal function,such as indicators.The severity of CAS was quantified in a...