| 轻度认知功能障碍患者血脂代谢的变化 |
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| 引用本文： | 朱红莲,潘志红,王根发.轻度认知功能障碍患者血脂代谢的变化[J].上海交通大学学报(医学版),2008,28(5):516-517. |
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| 作者姓名： | 朱红莲 潘志红 王根发 |
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| 作者单位： | 上海交通大学医学院新华医院老年科 上海200092 |
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| 摘 要： | 目的研究轻度认知功能障碍(MCI)患者血脂代谢的变化。方法测定并比较60例MCI患者和100例年龄相当的正常对照者(对照组)血清总胆固醇(TC)、甘油三脂(TG)、低密度脂蛋白(LDL)和高密度脂蛋白(HDL)水平。结果MCI患者TC、TG和LDL水平明显高于对照组,HDL水平明显低于对照组,差异有统计学意义(P<0.05)。结论MCI患者存在明显的脂质代谢紊乱,TC、TG和LDL水平的升高或HDL的降低可能对发病有一定的影响。
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| 关 键 词： | 轻度认知功能障碍 总胆固醇 甘油三脂 低密度脂蛋白 高密度脂蛋白 |
| 文章编号： | 0258-5898(2008)05-0516-02 |
| 修稿时间： | 2008年2月18日 |
Change of metabolism of serum lipids in patients with mild cognitive impairment |
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| ZHU Hong-lian,PAN Zhi-hong,WANG Gen-fa.Change of metabolism of serum lipids in patients with mild cognitive impairment[J].Journal of Shanghai Jiaotong University:Medical Science,2008,28(5):516-517. |
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| Authors: | ZHU Hong-lian PAN Zhi-hong WANG Gen-fa |
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| Abstract: | Objective To study the change of metabolism of serum lipids in patients with mild cognitive impairment(MCI). Methods The serum levels of total cholesterol(TC),triglyceride(TG),low density lipoprotein(LDL) and high density lipoprotein(HDL) were measured in 60 patients with MCI and 100 age-matched normal controls. ResultsThe serum levels of TC,TG and LDL were significantly higher and HDL significantly lower in patients with MCI than in normal controls(P<0.05). Conclusion Metabolic disturbance of serum lipids exists in patients with MCI.The increase of TC,TG and LDL and decrease of HDL may have effects on the onset of MCI. |
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| Keywords: | mild cognitive impairment total cholesterol triglyceride low density lipoprotein high density lipoprotein |
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