O/W型微乳对挥发油增溶作用的实验研究

目的：研究O/W型微乳对挥发油的增溶作用。方法：通过滴定法绘制拟三元相图，分别考察微乳对不同品种挥发油的增溶以及微乳处方对甜橙油增溶作用的影响。结果：相同的微乳配方可对多种挥发油产生增溶作用；微乳的油相和表面活性剂的品种、用量对甜橙油的增溶均有影响。结论：适宜的微乳处方可以增溶挥发油，为解决液体制剂中挥发油的稳定分散问题提供了实验依据。

Study on the solubilization of O/W microemulsion for volatile oil

Objective: To study the solubilization of O/W microemulsion system for volatile oil. Method: Pseudo-ternary phase diagrams were prepared by using the method of titration, then investigating the solubilization of microemulsion system for different kind of volatile oil was investigated with the diagrams, and the effect of the formulation of microemulsion on the solubilization of Citrus sinensis oil were studied. Result: Kinds of volatile oil havd an accelerated solubility in the microemulsion system. The species and dosage of oil phase and surfactant could influence the solubilization of microemulsion on Citrus sinensis oil. Conclusion: It is recommended to select a new method to solve the stabilization of volatile oil in the liquid preparation by the solubilization of suitable formulation of microemulsion.