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Selective nicotinic receptor antagonists: effects on attention and nicotine-induced attentional enhancement |
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| Authors: | Hahn Britta Shoaib Mohammed Stolerman Ian P |
| Affiliation: | (1) University of Maryland School of Medicine, Maryland Psychiatric Research Center, P.O. box 21247, Baltimore, MD 21228, USA;(2) Institute of Neuroscience, Newcastle University, Newcastle, NE24HH, UK;(3) Department of Addictions, Institute of Psychiatry P048, King’s College London, De Crespigny Park, London, SE5 8AF, UK |
| Abstract: | RationaleThe question of the subtype(s) of the nicotinic acetylcholine receptor (nAChR) mediating the attention-enhancing effects of nicotine is still unsettled. While early studies pointed towards subtypes other than the homomeric α7 nAChR, pro-cognitive effects of α7 nAChR agonists have since been demonstrated. |
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