海南地区急性胰腺炎病因学分析

目的 探讨海南地区急性胰腺炎的发病趋势、病因变化,为诊疗工作提供依据.方法 回顾性分析某院和白沙黎族自治县人民医院2001～2010年急性胰腺炎(AP)住院患者2 176例临床资料,并对结果进行统计分析.结果 2001～2005和2006～2010两个年度段,AP占住院人数的比例分别为0.46％ (831/179122),0.52％ (1345/260137) (P＜0.05)；胆源性AP分别为54.39％ (452/831),46.17％ (621/1345) (P＜ 0.05)；高脂血症性AP分别为8.54％ (71/831),13.01％ (175/1345) (P＜0.01);酒精性AP分别为11.43％ (95/831),13.83％ (186/1345) (P＞ 0.05).特发性AP分别为18.41％ (153/831),13.90％ (187/1345) (P＜ 0.05).结论 近10年AP发病持续增加,胆道疾病仍为主要病因,高脂血症性AP明显增多,酒精性AP无明显变化.

Analysis of etiology with acute pancreatitis in Hainan region

OBJECTIVE To explore the morbidity trend and etiology varieties of the acute pancreatitis in Hainan region so as to provide references for the clinical diagnosis and treatment of AP.METHODS Clinical data of 2 176 patients with AP who received treatment in Hainan Provincial People’s Hospital and Baisha County People’s Hospital between 2001 and 2010 were reviewed retrospectively,and statistical analysis to the data.RESULTS The composition ratio of AP in hospital between 2006 and 2010 was respectively 0.52%,higher than that in 2001-2005(0.46%).The difference between two groups showed a statistical significance(P﹤0.05).Base on etiology,biliary pancreatitis was 54.39% in 2001-2005,while 46.17% in 2006-2010(P﹤0.05);Hypertriglyceridemia pancreatitis were 8.54% and 13.01%(P﹤0.01)respectively in 2001-2005 and 2006-2010;Alcoholic pancreatitis were 11.43% and 13.83%(P﹥0.05)respectively in 2001-2005 and 2006-2010;Idiopathic pancreatitis were 18.41% and 13.90%(P﹤0.05)respectively in 2001-2005 and 2006-2010;Other factors of pancreatitis were 7.22% and 13.09% respectively in 2001-2005 and 2006-2010.CONCLUSION The incidence of AP has been increasing continuously in the past 10 years,the biliary tract disease is still a main etiology.Hypertriglyceridemic pancreatitis increases rapidly,not like alcoholic pancreatitis.