组织微阵列技术在运动医学研究中的应用进展

组织微阵列技术可实现高通量、并行性、大规模、快速准确的基因、蛋白质的原位可视化研究,并可分别在基因、基因的转录及其表达产物的生物学功能等3个水平上进行研究.本文综述了组织微阵列的原理、制作方法,在医学及其在运动医学中的运动性心肌肥大相关基因筛选、运动基因选材、运动性疲劳及运动损伤相关基因表达变化的研究进展.

Application and advancement on tissue microarrays technology in sports medicine

Study on the techniques for visualization in situ,tissue microarrays technology could implement high-flux,large scale,simultaneous treatment,quickly and precise of gene and protein.And gene,gene transcribe and expression were applied respectively in three levels by tissue microarrays.This article reviews application and advancement to gene screening of exercise induced cardiac hypertrophy,athlete gene selection,express change of sports fatigue related gene and gene of exercise injury.