| 肝病患者血清Lp（a）检测的临床意义 |
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| 引用本文： | 张阳根. 肝病患者血清Lp（a）检测的临床意义[J]. 现代诊断与治疗, 1995, 6(3): 146-147 |
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| 作者姓名： | 张阳根 |
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| 作者单位： | 解放军第１７５医院 |
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| 摘 要： | 测定急性肝炎、慢性肝炎、肝硬化和重症肝炎患者血清中脂蛋白（ａ）［ＰＬ（ａ）］的浓度，结果分别为１４１．３±９２．４、７２．４±４３．２、５４．７±３７．８和５０．９±４１．６ｍｇ／Ｌ，与正常对照组（１５５．６±９９．１ｍｇ／Ｌ）比较差异显著（Ｐ＜０．０５）．其含量随病情加重逐渐降低，与急性肝炎血清ＧＰＴ呈负相关（ｒ＝－０．２７８，Ｐ＜０．００１）．提示血清Ｌｐ（ａ）含量可作为反映肝脏合成功能和损害程度的指标之一。
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| 关 键 词： | 脂蛋白（a），肝炎、肝硬化 |
Determination of Serum Lipoprotein (a)and Its Clinical Significance in Patientswith Liver Diseases |
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| Zhang Yanggen. Determination of Serum Lipoprotein (a)and Its Clinical Significance in Patientswith Liver Diseases[J]. Modern Diagnosis & Treatment, 1995, 6(3): 146-147 |
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| Authors: | Zhang Yanggen |
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| Abstract: | The serum lipoprotein(a)in the pa-tients with acute hepatitis,chronic hepatitis,cirrho-sis and fulminant hepatitis was determined.The con-centrations were found to be 141.3±92.4mg/L,72.4±43.2mg/L,54.7±37.8mg/L and 50.9±41.6mg/L respectively, There was a significant differencecompared with the control group(155.6±99.1mg/L,P<0.05).The level of serum lipoprotein(a)wasgradually decreased according to the severity of liverdisease and there was a negative correlation with theserum GPT in acute hepatitis (r=-0. 278, P<0.001).The results showed that the level of serumlipoprotein (a)can be one of the markers to evaluatethe synthetic functions and the severity of the dam-age in liver. |
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| Keywords: | Lipoprotein(a)Hepatitis Cir-rhosis |
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