抗生素骨水泥治疗创伤性胫骨骨髓炎的创面愈合效果

目的探讨抗生素骨水泥治疗创伤性胫骨骨髓炎患者的临床效果。方法 96创伤性胫骨骨髓炎患者,依据患者入院单双号分为观察组和常规组,每组48例。常规组患者给予局部抗生素灌注治疗,观察组患者给予局部抗生素骨水泥治疗。比较两组患者治疗效果、并发症发生率、骨缺损长度、软组织缺损面积及手术前后疼痛评分。结果观察组患者总有效率为97.92%,常规组总有效率为85.42%;观察组患者总有效率明显高于常规组,差异有统计学意义(P<0.05)。观察组患者骨缺损长度为(1.42±0.23)cm,软组织缺损面积为(0.76±0.25)cm^2;常规组患者骨缺损长度为(1.79±0.37)cm,软组织缺损面积为(0.99±0.48)cm^2;观察组患者骨缺损长度及软组织缺损面积均优于常规组,差异有统计学意义(P<0.05)。手术前,两组患者疼痛评分比较差异无统计学意义(P>0.05);手术后,观察组患者疼痛评分(2.47±0.79)分显著低于常规组的(3.85±0.98)分,差异有统计学意义(P<0.05)。观察组患者并发症发生率6.25%低于常规组的25.00%,差异有统计学意义(P<0.05)。结论对于创伤性胫骨骨髓炎患者在临床上可以根据患者病情发展的实际情况采取抗生素骨水泥治疗,一方面能够促进患者临床治疗效果的提升,另一方面还可有效减少骨缺损的长度、面积,降低并发症发生率,有较高的使用和推广价值。

Effect of antibiotic bone cement on wound healing of traumatic tibial osteomyelitis

Objective To discuss the clinical effect of antibiotic bone cement on wound healing of traumatic tibial osteomyelitis.Methods A total of 96 traumatic tibial osteomyelitis patients were divided into observation group and conventional group by odd-even number of admission,with 48 cases in each group.The conventional group was treated by local antibiotic perfusion,and the observation group was treated by local antibiotic bone cement.The therapeutic effect,incidence of complications,bone defect length,soft tissue defect area and pain score before and after operation was compared between the two groups.Results The total effective rate was 97.92%in the observation group,which was 85.42%in the conventional group.The total effective rate in the observation group was obviously higher than that in the conventional group,and the difference was statistically significant(P<0.05).The bone defect length was(1.42±0.23)cm,soft tissue defect area was(0.76±0.25)cm^2 in the observation group,which was(1.79±0.37)cm and(0.99±0.48)cm^2 in the conventional group.The bone defect length and soft tissue defect area in the observation group was better than those in the conventional group,and their difference was statistically significant(P<0.05).Before operation,there was no statistically significant difference in pain score between the two groups(P>0.05).After operation,the pain score(2.47±0.79)points in the observation group was significantly lower than(3.85±0.98)points in the conventional group,and the difference was statistically significant(P<0.05).The incidence of complications 6.25%in the observation group was lower than 25.00%in the conventional group,and the difference was statistically significant(P<0.05).Conclusion For the patients with traumatic tibial osteomyelitis,antibiotic bone cement treatment can be used according to the actual situation of the patients,it can not only promote the improvement of the clinical treatment effect,but also effectively reduce the length and area of the bone defect,lower the incidence of complications.It has high application and promotion value.