Herbal medicines and nonalcoholic fatty liver disease |
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Authors: | Hong Yao Yu-Jie Qiao Ya-Li Zhao Xu-Feng Tao Li-Na Xu Lian-Hong Yin Yan Qi Jin-Yong Peng |
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Institution: | Hong Yao, Yu-Jie Qiao, Ya-Li Zhao, Xu-Feng Tao, Li-Na Xu, Lian-Hong Yin, Yan Qi, Jin-Yong Peng, College of Pharmacy, Dalian Medical University, Dalian 116044, Liaoning Province, China |
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Abstract: | Nonalcoholic fatty liver disease(NAFLD), which is characterized by excessive fat accumulation in the liver of patients who consume little or no alcohol, becomes increasingly common with rapid economic development. Long-term excess fat accumulation leads to NAFLD and represents a global health problem with no effective therapeutic approach. NAFLD is considered to be a series of complex, multifaceted pathological processes involving oxidative stress, inflammation, apoptosis, and metabolism. Over the past decades, herbal medicines have garnered growing attention as potential therapeutic agents to prevent and treat NAFLD, due to their high efficacy and low risk of side effects. In this review, we evaluate the use of herbal medicines(including traditional Chinese herbal formulas, crude extracts from medicinal plants, and pure natural products) to treat NAFLD. These herbal medicines are natural resources that can inform innovative drug research and the development of treatments for NAFLD in the future. |
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Keywords: | Herbal medicines Nonalcoholic fatty liver disease Natural product Traditional Chinese medicines Review |
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