双眼睑巨大结节状黄色瘤临床及病理分析（附1例报告）

目的探讨双眼睑巨大结节状黄色瘤的临床、病理特点,发病机制及治疗原则。方法结合文献分析双眼睑巨大结节状黄色瘤的临床、病理特点和治疗过程。结果眼睑巨大结节状黄色瘤病人常有血脂代谢异常,可有血糖异常,伴身体其他部位黄色瘤。病变均侵及真皮及真皮下结缔组织和眼轮匝肌,组织病理学示皮下或真皮内大量泡沫状组织细胞和黄瘤巨细胞（Touton巨细胞）,切片苏丹染色,胞浆内充满脂滴,病理学均诊断为眼睑结节状黄色瘤。结论眼睑巨大结节状黄色瘤的诊断除依据临床表现外,主要依据病理学诊断,其发病原因和机制尚不明了,治疗方法首选手术切除。

CLINICAL AND PATHOLOGICAL STUDY ON HUGE TUBEROUS XANTHOMA OF BOTH EYELIDS： A REPORT OF ONE CASE

Objective To study the clinical and pathological features, pathogenesis and therapeutic principle of tuberous xanthoma of both eyelids. Methods The clinical and pathological characteristics and treatment of the case was analyzed with reference of literatures. Results Abnormal lipid metabolism, abnormal blood glucose, and xanthoma on other parts of the body were commonly seen in patients with the disease. Dermis, subcutaneous connective tissue and orbicularis oculi muscle were in volved. Histopathologieally, substantial bubble-shaped yellow giant cell tissue and Touton giant ceils were observed. Conclusion The diagnosis of this disease mainly based on pathology apart from clinical manifestations. The pathogenesis is not clear. Surgical resection is the first of choice.