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抗高血压药物对牙龈增生的影响
引用本文:马玉芬,胡伟忠,王钰莹,胡伟平. 抗高血压药物对牙龈增生的影响[J]. 中国现代医生, 2011, 49(10): 9-10
作者姓名:马玉芬  胡伟忠  王钰莹  胡伟平
作者单位:1. 锦州市太和区营盘乡口腔诊所,辽宁锦州,121000
2. 哈尔滨医科大学附属第二医院口腔科,黑龙江哈尔滨,150086
摘    要:目的研究钙离子通道阻滞剂(CCBs)与肾素血管紧张素系统(RAS)药物抗高血压治疗中伴发牙龈增生的风险率。方法对使用任一种CCBs药物与肾素-血管紧张素(RAS)相互作用的患者作病例对照研究。研究组为确诊牙龈增生的患者。对照组按其性别、年龄、症状出现的标准日期与研究组进行配比。结果研究对象中,有102例发生牙龈增生,使用CCBs者牙龈增生风险率较高,OR值:1.7,95%可信区间为:1.0~3.1。同时使用CCBs和RAS对牙龈增生有双重风险,OR值:2.1,95%可信区间为:0.8~4.2。结论服用CCBs和RAS药物均可伴发牙龈增生。CCBs比RAS药物对牙龈增生影响较大。

关 键 词:牙龈增生  药物性牙龈增生  钙离子通道阻滞剂  血管紧张素系统

Effect of Anti-hypertensive Medication on the Risk of Gingival Hyperplasia
MA Yufen,HU Weizhong,WANG Yuying,HU Weiping. Effect of Anti-hypertensive Medication on the Risk of Gingival Hyperplasia[J]. Journal China Modern Doctor, 2011, 49(10): 9-10
Authors:MA Yufen  HU Weizhong  WANG Yuying  HU Weiping
Affiliation:MA Yufen1 HU Weizhong1 WANG Yuying2 HU Weiping2 1.Dental Clinic of Taihe District Panying Township of Jinzhou City,Jinzhou 121000,China,2.Department of Stomatology,the Second Affiliated Hospital of Harbin Medical University,Harbin 150086
Abstract:Objective To study the effect of calcium channel blockers(CCBs) and rennin-angiotensin system(RAS) on the risk of gingival hyperplasia.Methods Patients were studied who were treated with either calcium channel blockers or rennin-angiotensin.Patients with gingival hyperplasia were divided into study group.Gender,age and the date of symptom appearing in two groups were matched.Results There were 102 cases with gingival hyperplasia.The risk of gingival hyperplasia was higher in CCBs than in CCBs,OR:1.7,95% con...
Keywords:Gingival hyperplasia  Drug-induced gingival overgrowth  Calcium channel blockers(CCBs)  Renin-angiotensin system  
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