| 银荆感冒颗粒解热作用的实验研究 |
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| 引用本文： | 王训乐,邱召娟,朱萱萱,严士海. 银荆感冒颗粒解热作用的实验研究[J]. 东南大学学报(医学版), 2008, 27(1): 10-12 |
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| 作者姓名： | 王训乐 邱召娟 朱萱萱 严士海 |
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| 作者单位： | 南京医科大学附属第二医院,药剂科,江苏,南京,210029;江苏省中医院,江苏,南京,210029 |
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| 基金项目： | 江苏省中医药管理局科研项目 |
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| 摘 要： | 目的:研究银荆感冒颗粒的解热作用.方法:将54只SD大鼠随机分成模型组,正柴胡颗粒组,扑热息痛组及银荆感冒颗粒小、中、大剂量组,每组9只.末次给药后,大鼠背部皮下注射2,4-二硝基苯酚,测量大鼠体温的变化情况;大鼠后脚两爪脚跖皮下注射角叉莱胶悬液,测量其肛温的变化情况.结果:(1)银荆感冒颗粒小、中、大剂量组对2,4-二硝基苯酚所致大鼠发热解热作用的持续时间分别为120、150、180 min以上;(2)银荆感冒颗粒小、中、大剂量组对角叉莱胶所致大鼠发热的解热作用的持续时间分别为4、5、6 h.结论:银荆感冒颗粒具有较好的解热作用.
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| 关 键 词： | 银荆感冒颗粒 2 4-二硝基苯酚 角叉莱胶 解热 |
| 文章编号： | 1671-6264（2008）02-0010-03 |
| 收稿时间： | 2007-09-25 |
| 修稿时间： | 2007-09-25 |
Study on the effect of Yinjingganmao grains on reliefing fever |
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| WANG Xun-le,QIU Shao-juan,ZHU Xuan-xuan,YAN Shi-hai. Study on the effect of Yinjingganmao grains on reliefing fever[J]. Journal of Southeast Univ: Medical Sci Ed, 2008, 27(1): 10-12 |
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| Authors: | WANG Xun-le QIU Shao-juan ZHU Xuan-xuan YAN Shi-hai |
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| Abstract: | Objective To study the effect of Yinjingganmao grains to relieve fever.Methods(1)The rats were given Yinjingganmao grains for 7 days.On the last day,the rats were injected subcutaneouly on their back with dinitrophenol and the body temperature of rat was measured.(2)The rats were given Yinjingganmao grains for 7 days.On the last day,the rats were injected subcutaneouly on the foot plate of crus curvilineum with SN-263 and the anus temperature of rat was measured.Results Yinjingganmao grains relieved fever caused by dinitrophenol lasting 120,150 and 180 min respectively in the three groups,while fever caused by SN-263 was relieved for 4,5,6 h respectively.Conclusion Yinjingganmao gains significantly relieve fever. |
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| Keywords: | Yinjingganmao grains dinitrophenol SN-263 fever relief |
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