大型前中颅窝颅底沟通瘤的显微手术切除与颅底重建

本文报告7例大型前中颅窝沟通瘤,其中3例肿瘤直径超过11cm,全组病人均采用显微神经外科手术一次全切肿瘤,同时行颅底重建,全组病人均治愈.经7个月～4.5年随访,无肿瘤复发.作者指出,认真处理供瘤血管,分块切除肿瘤,保护重要血管和神经,根据颅底骨质缺损大小采取相应重建方法是确保手术成功的关键.另外,强调根据肿瘤生长特性及发展方向选择手术入路,有助于显露及全切肿瘤.

Microsurgical treatment and reconstruction of skull base on large communicating tumors of anterior and middle skull base

Seven cases with large communicating tumors in the anterior and middle skull base underwent microsurgical treatment and one stage reconstruction of skull base were reported. The diameter of the tumors in 3 patients was more than 11cm. All patients were cured after operation. No recurrence by 7 months to 4. 5 years fol-lowing up postoperatively was found. The authors point out that it is important to obliterate the feeding vessels carefully,and remove the tumor piece by piece,to protect the functional vessels and cranial nerves, repair of dural mater defect and bony defect of skull base by means of proper methods. The authors also emphasized that according to the size and location of the tumor, it is important to select an appropriate approach which is good for creating a broad access to the skull base for removing the tumors.