Serial changes of liver stiffness measured by acoustic radiation force impulse imaging in acute liver failure: a case report |
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| Authors: | Kuroda Hidekatsu Takikawa Yasuhiro Onodera Mio Kakisaka Keisuke Yoshida Yuichi Kataoka Koujiro Sawara Kei Miyamoto Yasuhiro Oikawa Kanta Endo Ryujin Suzuki Kazuyuki |
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| Institution: | Division of Gastroenterology and Hepatology, Department of Internal Medicine, Iwate Medical University, School of Medicine, Uchimaru 19-1, Morioka, Iwate, 020-8505, Japan. |
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| Abstract: | Acoustic radiation force impulse (ARFI) imaging is a new technology used to determine liver elasticity. We report the case of a patient that survived hyperacute-type acute liver failure (ALF) and who showed a dramatic change in the value of shear wave velocity (SWV) measured by ARFI, which corresponded with the severity of her liver damage. The value of SWV increased significantly up to 3.6 ± 0.3 m/s during the encephalopathy phase and then decreased along with the recovery of liver function, the blood flow of the right portal vein, and the liver volume. These findings suggest the value of SWV in ALF as a reliable marker of liver tissue damage. Further investigations of the pathophysiological significance of SWV in ALF are warranted. |
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| Keywords: | acute liver failure liver stiffness ARFI shear wave velocity elastography |
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