Clinical and radiological observation in a surgical series of 36 cases of fibrous dysplasia of the skull |
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Authors: | Cai MingJun Ma LianTing Xu GuoZheng Gruen Peter Li Jun Yang Ming Pan Li Guan HanFeng Chen Gang Gong Jie Hu JunMing Qin ShangZheng |
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Affiliation: | Department of Neurosurgery, Wuhan General Hospital of Guangzhou Military Command, 627 Wuluo Avenue, Wuhan, Hubei 430070, PR China. mingjuncai@hotmail.com |
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Abstract: | ObjectivesTo describe the clinical and radiological findings in a consecutive series of patients diagnosed with fibrous dysplasia of the skull.Patients and methodsA retrospective analysis of collected data for 36 patients with histopathologically confirmed fibrous dysplasia involving the skull is presented. The demographic data, clinical presentation, radiographic characteristics, and the management of these patients were reviewed.ResultsAll 36 patients in this review were diagnosed with fibrous dysplasia involving at least part of the skull. In this study, the most commonly involved area of the skull was the frontal bone (52.78% of patients). The next most common area of skull was the temporal bone (30.56% of patients), followed by the sphenoid bone (25% of patients), the parietal bone (19.44% of patients), and orbital bone (13.89% of patients). The principal clinical presentation included headache, local lump, exophthalmos, visual disorder, cranial nerve paralysis, and facial malformation. These patients were treated by surgical treatment, and several of our patients underwent various degrees of reconstruction to optimize function.ConclusionsEffective surgical treatment may improve the short-term outcome in these patients, and a “tailored” surgical approach is necessary. |
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Keywords: | Fibrous dysplasia Skull Computed tomography Magnetic resonance imaging Surgery |
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