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孕期甲胎蛋白持续增高对围产儿结局的影响
引用本文:牛英慧,张东红,李春燕,贺杰,李莉.孕期甲胎蛋白持续增高对围产儿结局的影响[J].中国妇幼保健,2011,26(35):5520-5521.
作者姓名:牛英慧  张东红  李春燕  贺杰  李莉
作者单位:1. 河北省邯郸市妇幼保健院 056001
2. 邯郸市峰峰矿区妇幼保健院
基金项目:河北省邯郸市计划内课题项目〔1020108099-6〕
摘    要:目的:探讨孕妇血清甲胎蛋白值持续增高与胎儿宫内缺氧及围产儿预后的关系。方法:以2006年7月~2010年6月门诊建立孕妇保健手册、检测血清甲胎蛋白值持续增高的76例孕妇作为观察对象(监测组),随机抽取同期建卡的孕妇150例作为对照组,比较两组胎儿宫内窘迫、新生儿窒息、新生儿缺血缺氧性脑病的发生率及剖宫产率。结果:监测组胎儿宫内窘迫、新生儿窒息、新生儿缺血缺氧性脑病的发生率均明显高于对照组(P<0.05),其剖宫产率亦高于对照组(P<0.01)。结论:孕妇甲胎蛋白持续增高提示胎儿存在宫内缺氧,需及时予以改善宫腔内环境及缺氧状态,临产时应放宽手术指征,尽快结束妊娠并对新生儿及时进行治疗,以减少围产儿不良结局。

关 键 词:甲胎蛋白  胎儿窘迫  围产儿结局  缺血缺氧性脑病

Effect of continuous increase of alpha fetoprotein during pregnancy on perinatal outcome
NIU Ying-Hui,ZHANG Dong-Hong,LI Chun-Yan et al.Maternal , Child Health Hospital of H,an City,H,an ,Hebei,China.Effect of continuous increase of alpha fetoprotein during pregnancy on perinatal outcome[J].Maternal and Child Health Care of China,2011,26(35):5520-5521.
Authors:NIU Ying-Hui  ZHANG Dong-Hong  LI Chun-Yan Maternal  Child Health Hospital of H  an City  H  an  Hebei  China
Institution:NIU Ying-Hui,ZHANG Dong-Hong,LI Chun-Yan et al.Maternal and Child Health Hospital of Handan City,Handan 056001,Hebei,China
Abstract:Objective:To explore the relationship between continuous increase of alpha fetoprotein and intrauterine hypoxia of fetuses and prognosis of perinatal infants. Methods:76 pregnant women who built maternal health care handbooks in outpatient department of the hospital from July 2006 to June 2010 were selected as study objects,their serum alpha fetoprotein values increased continuously;150 pregnant women who built maternal health care handbooks at the same time were selected randomly as control group.The incid...
Keywords:Alpha-fetoprotein  Fetal distress  Perinatal outcome  Hypoxic ischemic encephalopathy  
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