Incorporation of vancomycin-supplemented bone incorporation of vancomycin-supplemented bone allografts: radiographical, histopathological and immunohistochemical study in pigs |
| |
| Authors: | Buttaro Martin A González Della Valle Alejandro M Piñeiro Laura Mocetti Esteban Morandi Ana A Piccaluga Francisco |
| |
| Affiliation: | Institute of Orthopaedics Carlos E. Ottolenghi, Hospital ltaliano de Buenos Aires, Argentina. cadera@hospitalitaliano.org.ar |
| |
| Abstract: | We compared the incorporation of bone allografts with or without vancomycin in tibial defects of 18 pigs. High-quality radiographs, histological examination, immunological expression of metalloproteinase-13 (MMP-13) and transforming growth factor-beta 2 (TGFbeta2) indicated that there was no significant difference in bone allograft incorporation between up to 220 times the MIC (minimum inhibitory concentration) in bone allografts with 1 g of vancomycin in each 300 g of allograft or without this supplement. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
