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湖南尖吻腹蛇纤维蛋白溶解酶对高粘血症和脑血栓形成患者血液流变学的影响
引用本文:成春英,黄志坚,于桂榕,李健荣,胡隆梅,万腊香,杨和平. 湖南尖吻腹蛇纤维蛋白溶解酶对高粘血症和脑血栓形成患者血液流变学的影响[J]. 中国动脉硬化杂志, 1995, 3(4): 314-316
作者姓名:成春英  黄志坚  于桂榕  李健荣  胡隆梅  万腊香  杨和平
作者单位:衡阳医学院分子生物学研究中心,郴州医学专科学校生理学教研室,上海航天中心医院,广州军区南岳制药厂
摘    要:本文报告湖南尖吻腹蛇纤维蛋白溶解酶(简称蛇纤溶酶)对23例单纯高粘血症和31例脑血栓形成患者血液流变学的影响。结果发现蛇纤溶酶能够使高粘血症患者全血比粘度低切变、血沉和血沉方程K值、红细胞聚集指数、纤维蛋白原和血浆比粘度降低,使脑血栓形成患者的指甲床微循环得到改善。这些结果提示,湖南尖吻腹蛇纤维蛋白溶解酶有降低血液粘度,使栓塞血管再通和改善微循环的功能。可用来治疗血栓性血管病。

关 键 词:湖南尖吻腹蛇;纤维蛋白溶解酶;高粘血症;脑血栓形成;血液流变学
收稿时间:1995-11-23

The Effect of Fibrinolysin from Hunan Agkistrodon Acutus on Hemorheology in Patients with Hyperviscosaemia and Cerebral Thrombosis
CHENG Chun-Ying,HUANG Zhi-Jian,YU Gui-Rong,LI Jian-Rong,HU Long-Mei,WAN La-Xiang and YANG He-Ping. The Effect of Fibrinolysin from Hunan Agkistrodon Acutus on Hemorheology in Patients with Hyperviscosaemia and Cerebral Thrombosis[J]. Chinese Journal of Arteriosclerosis, 1995, 3(4): 314-316
Authors:CHENG Chun-Ying  HUANG Zhi-Jian  YU Gui-Rong  LI Jian-Rong  HU Long-Mei  WAN La-Xiang  YANG He-Ping
Affiliation:Molecular Biological Center, Hengyang Medical College, Hengyang 421001. Department of Physiology,Qingzhou Medical training School, Hunan 423000.Spaceflight Center Hospital, Shanghai 200001.Nanyao Pharmaceutical Factory,Hengyang 421007,China
Abstract:The paper reported the effect of fibrinolysin from Hunan Agkistrodon acutus on hemorheology in 23 cases of hyperviscosaemia and 31 cases of cerebral thrombosis. It is found that the flbrinolysin from Hunan Agkistrodon acutus may reduce low shear of blood specific viscosity, erythrocyte sedimentation rate (ESR),equation K value of ESR,and aggregative index of red blood cell, fibrinogen and plasma specific viscosity in patients with hyperviscosaemia and improve microcirculation of hyponychium in patients with cerebral thrombosis.This results indicate that the fibrinolysin may be used to treat these diseases.
Keywords:Hunan Agkistrodon Acutus  Fibrinolysin  Hyperviscosaemia  Cerebral thrombosis  Hemorheology  
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