兰州地区前列腺增生和前列腺癌发病情况及发病因素分析

为了解兰州地区前列腺增生 (BPH)和前列腺癌的发病情况 ,调查了该地区 5 0岁以上男性 135 6人的国际前列腺症状评分 (I-PSS)、生活质量评分 (L)、前列腺体积 (V)、直肠指检等情况 ,测量了 14 5人血清睾酮 (T)、前列腺特异抗原 (PSA)。结果显示 ,BPH发病率占总调查人数的 35 .0 3% (4 75 / 135 6 ) ,城市人口发病率 4 1.0 4 %(2 5 2 / 6 14 ) ,农村人口发病率 30 .0 5 % (2 2 3/ 74 2 ) ;城市人口明显高于农村 (P <0 .0 5 )。前列腺癌占总调查人数的2 .5 0 % (34/ 135 6 ) ;城市职工 3.0 9% ,农村人口 2 .0 2 % ;城市人口同样高于农村人口。前列腺癌组PSA明显高于正常对照组 (P <0 .0 5 )。结论 :城镇职工的BPH和前列腺癌的发病率高于农村人口 ,与年龄、城乡地区、饮食结构有关 ,已成为常见的老年病

Prevalence of Benign Prostatic Hyperplasia and Prostate Cancer and Its Relative Factors in Lanzhou

To investigate the benign prostatic hyperplasia (BPH) and prostate cancer in Lanzhou,an investigation of the incidence of BPH and prostate cancer in 1356 male inhabitants over 50 years of age has been carried out including I-PSS,life quality (L), volume of prostate (V) and digital rectal examination. Plasma testosterone(T) and prostate specific antigen(PSA) were assayed in 145 cases. The incidence of BPH was 35.03%, being 41.04% in urban and 30.05% in rural inhabitants. The increase of BPH has been higher in urban inbabitants ( P <0.05).The incidence of prostate cancer was 2.05%,being 3.09% in urban and 2.02% in rural inhabitants,the increase of prostate cancer has been higher in urban inhabitants ( P <0.05).A significant increase of prostate specific antigen was noted in prostate cancer patients ( P <0.05).Conclusions: The increase of BPH and prostate cancer has been higher in urban inhabitants.The age, diet and residential areas might associate with a higher incidence of BPH and prostate cancer.